Excerpts

Our data for PD and non-neurologic controls shows wide intra-group variability and yet the differences between KS30, AT30 and IS30 are highly significant and of clinically relevant magnitude, enabling cut-offs for sensitivity and specificity to be determined.

Injection of AAV2.sIL17R resulted in sIL17R protein expression, no change in retinal Il17a transcripts, and a near-significant reduction in Il6 ( Figure S1C–E ), supporting sIL17R expression in AAV2.sIL17R- but not in AAV2.EV-treated eyes.

However, an increasing trend was observed in the IgG level of Blasto and Blasto-Stressed groups with a significant difference when compared to the normal group especially at week 4 (P<0·05).

Other reliability studies found evidence of non-uniform variability in cortical thickness measurements when comparing different processing conditions such as workstation or FreeSurfer version [26] and highly significant differences were reported predominantly in the frontal and temporal cortices.

Five dogs showed a trend towards an increase in apoptosis following treatment ( Fig 6B ).

Abstract Introduction In India there is an increasing trend in hypertension prevalence among the general population.

Furthermore, the span of both computed energies for which experimental data are available (20 kcal/mol) and the values (2 orders of magnitude) is too small to allow a clear trend.

A clear trend was evident in the percent female with fish length, decreasing steadily from 74–89% in the 150 and 155 cm length classes to only 7–27% in the 185 and 190 cm length classes.

Results from the GLMs suggest that spawning season, month and BE index are all highly significant explanatory variables of the proportion of small SBT, as are the pair-wise interaction terms between spawning season and month and spawning season and BE index ( Table 3 ).

Analogical to this, when two or more non-significant comparisons are described, only the values of the comparison that approached significance the most are reported.

The odds of IPD were increased by 9% in studies using culture as well as LAT as diagnostic modalities when compared to studies using culture testing alone, and this association showed a trend toward significance (OR 1.09; 95% CI: 0.99–1.21).

Similarly, in mice immunized with 6OXY-TT, alum showed a trend of eliciting higher TT-specific serum IgG titers compared to MPLA ( Figure 6 , panel B).

Phosphorylation of p53 S20 was not readily detectable, but p21 Cip1 levels showed a trend towards being elevated in SV40 immortalized Poldip2−/− MEFs, similar to untransformed Poldip2−/− MEFs ( Figure 8D and 5D ).

While the A2 climate change scenario shows an overall trend of higher flows, its flow duration curve drops sharply below the baseline at 90% exceedance, suggesting that under this scenario of climate change much lower flows will be experienced during drought periods.

The full models of both analyses (model 7) show that the effect of ethnic minority density on the outcome variables, as well as the interaction term of ethnic minority density and non-Western ethnicity, remains stable and highly significant.

The only other relevant variable in the model that showed a significant trend was western style fast food consumption in 2005 (p 0.007).

Spearman's rank correlation coefficients (ρ) of TV+, TV and CETV showed highly significant correlations between automatic and manual segmentations.

Conversely, production of CCL2 was significantly augmented in the COPD subjects, and CCL3 showed a trend towards increased production, which did not attain statistical significance ( Fig. 1B, 1C ) .

When strictly applying the Bonferroni correction needed to adjust for the multiplicity of 10 parallel cytokine measurements, the difference in IFN-γ levels did not quite reach statistical significance.

Our current data are consistent with these outcomes, in that WP1066 shows a strong trend to inhibit Reg1 in gastric tumours of the gp130 757FF mouse along with IL-6 and IL-11 inhibition.

However, after indexation to BSA, this difference disappeared in our as well other studies [29] , although one study showed a trend toward higher LVDD/BSA values in women compared with men [28] .

The association between ‘number of paired teeth’ and height showed a positive trend across quintiles in males, whereas no relationship was evident in females ( Figure 1a and 1b respectively).

Water column TDOC was closely correlated with water column TDN (r = 0.92, p < 2.2e-16; Figure 2 ), while water column TDP exhibited a much weaker relationship with TDOC (r = 0.27, p = 8.0e-11; Figure 2 ).TDOC did not exhibit a strong trend across the season ( Figure S2 ).

Highly significant increases (over 1000-fold) in IL-8 and IL-6 transcripts and significant increases in TNF (2-fold) in HD patient post-mortem striatal tissue have been reported in independent studies [10] .

Table S4 Permutation analysis of the association matrix shown in Table S2 to find out if species with shared family and fruit types show more or less significant associations than expected by random distribution of significant cases over all pairs of species. n t : total number of significant associations of specified type; m t : total number of pairs with shared family or fruit type; n s : number of pairs with shared family or fruit type which show a significant association; n s exp : expectation of n s under 10,000 randomization of significant cases over all pairs of species.