Excerpts

This effect was accompanied by a highly significant increase in mobility of α7-nAChRs residing on dendrites (from 0.018±0.024 to 0.025±0.027 μm 2 /s; t = 5.015 df = 1352, p = 0.0023) whereas axonal QDs exhibited a moderate reduction in mobility (from 0.218±0.104 to 0.187±0.04 μm 2 /s; t = 2.811 df = 289, p = 0.0103) ( Fig. 6A ).

Weaker, though nominally significant associations were confirmed at IKZF1 (p = 2.3×10 −3 for G1N), SLC38A10 (p = 4.8×10 −3 for G2N), IL6ST-ANKRD55 (p = 1.3×10 −2 for G0N) and ABCF2-SMARCD3 (p = 2.7×10 −2 for G2N).

We observed a highly significant difference in the frequency of stenoses between 30% and 50% DS between the PAPS group ( n = 24) and the control group ( n = 7) (CI95: 0.59–0.90, p = 0.0023), as well as the SAPS group ( n = 30) (CI95: 0.65–0.92, p = 0.0002).

As shown in Figure 1 E, we found a highly significant inverse correlation between FOXM1 and the OS in both cohorts (Log rank test, p = 0.0023 and <0.00010, respectively).

Western blot analysis confirmed that ABHD6 protein levels were consistent across all samples, whereas gel‐based ABPP analysis revealed that ABHD6 activity was significantly lower in resilient individuals, with a negative trend in AD donors (Figure 4G‐I , Figure S4 : resilient vs control, p = 0.0023; AD vs control, p = 0.068, AD vs resilient, p = 0.089).

Indeed, if the same model is constructed without E3, the trend becomes highly significant ( p -value = 0.0023), and the adjusted R 2 is much improved (0.86).

The statistical comparison of net changes in gametocytaemia between treatments revealed a highly significant interaction between exposure and sampling day (model 3, time * exposure : χ 2 8 = 23.946, p = 0.0023) ( figure 1C ).

11 , where P < 0.05 is nominally significant; specific area significance (i.e., Specific brain thickness P < (0.05)/(11 traits*2 SNPs) = P < 0.0023.

At week 12, these increases were dose‐dependent and were significant for solriamfetol 300 mg (84.7%) and 150 mg (78.2%) doses versus placebo (39.7%; both p < 0.0001); the 75 mg dose was nominally significant (67.8%) compared with placebo ( p = 0.0023, but the comparison was below the hierarchical break).

As showed in Figure 3 , all the Amsel criteria showed a decreasing trend in Active group at T1 sampling time compared to T0 (Clue cell presence p -value = 0.0023; Homogenous vaginal discharge p -value = 3.05 × 10 −5 ; Positive amine test p -value = 0.0018; Vaginal pH > 4.5 p -value = 0.049).

This resulted in a highly significant difference in favor of ECT (chi sq = 9.267, p = 0.0023) [ 38 ].

The linear correlation of the in vivo and in vitro measures from brains with both procedures was highly significant (R 2 = 0.709, P = 0.0023; Fig. 3F ).

reported that addition of bevacizumab to oxaliplatin-based chemotherapy significantly improved PFS, although OS did not reach statistical significance, and the RR was not improved (PFS: 9.4 vs. 8.0 months [HR: 0.83; P = 0.0023], OS: 21.3 vs. 19.9 months [HR: 0.89; P = 0.077]) [ 7 ].

Here, the results of dosage meta-regression were highly significant ( β = 0.0013, p = 0.0023): the likelihood of an adverse event was strongly related to the dose of CBD.

The results demonstrated that MX2 displayed the most significant eQTL with rs398206 ( P = 6.6e−15; linear regression), while none of the other genes in the TAD displayed even a marginally significant eQTL after adjusting for multiple testing (Bonferroni-corrected cutoff at P < 0.0024 for 21 genes; Supplementary Table 9 ).

In the presence of 10 μM ENDF1, 37.1 ± 5.4% of the DRG neurons regrow their neurites, which was a highly significant increase compared to the vehicle condition ( p = 0.0024).

The scenarios are presented below: Markers that were 25 kb of a moderately significant DE genes ( p ≤ 2.4 × 10 −3 ); Markers that were 100 kb of a moderately significant DE genes ( p ≤ 2.4 × 10 −3 ); Markers that were 25 kb of a highly significant DE genes ( p ≤ 1.0 × 10 −4 ); Markers that were 100 kb of a highly significant DE genes ( p ≤ 1.0 × 10 −4 ); For scenarios i, ii, iii, and iv, the number of markers used to construct G DE were 864, 2,317, 354, and 941.

A two-way factorial ANOVA including populations and RHT-B1 alleles as factors showed a highly significant interaction ( P = 0.0024), confirming that the height difference between RHT-B1a and RHT-B1b was significantly larger than that between RHT-B1b E529K and RHT-B1b.

In untreated multiple sclerosis patients, the myeloid cell subset showed a trend for decreased CD40 MFI ( P = 0.0024) ( Supplementary Fig. 10 ).

In five of these six studies, p.E40K was associated with lower fasting glucose, and nominally significant association with fasting glucose was observed in meta-analysis of these six studies ( p = 0.0024, total n = 120,050).

Self-reported motivational processes in its present and retrospective versions correlated highly significant (r = .60, p < .0024) as well as informant-reported motivational processes in its present and retrospective versions (r = .35, p < .0024).

Statistical Analysis of the Challenge Data Through ANOVA Studies Samples displayed extremely significant difference between groups compared to control group with p -value less than 0.01 upon all the time points observed [ A. hydrophila ( p = 0.0024), AMS ( p = 0.0004), LAB ( p = 0.0001), LABS ( p = 0.0001), MOS ( p < 0.0001), SERUM ( p < 0.0001)].

Resveratrol pretreatment also had a highly significant effect in lowering the seizure score from approximately 5 to 2 min (Figure 3A ) and delayed seizure onset time from around 4 min to about 8 min ( P = 0.0024) (Figure 3B ).

A statistical trend was observed for P3 latency and the EDSS variable, r = 0.638, p = 0.0024).

Despite the low number of cases and non-estimable data, a highly significant ( p = 0.0024) relationship between the BG and the time to relapse for VC was found.