After 12 weeks of treatment in the DANISH study, the biomarker levels showed a numerical trend to be lower or equal in BASDAI50 responders vs non-responders, in patients with ASDAS ≥ CII, ASDAS CII, or ASDAS MI vs ASDAS NI, respectively.
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After achieving an initial clinical response, similar proportions of patients randomized to either therapy maintained their week 26 CDAI and DAS28(CRP) responses during 6-month follow-up, with a numerical trend favouring initial upadacitinib treatment across most disease activity measures ( Fig. 6 ).
Nonetheless, there is a numerical trend broadly in line with what we found in Experiment 1: ORCs had higher RTs than SRCs. 4.5.
In summary, the trials have shown a lower rate of adverse outcomes in initially invasive strategy driven by a decreased need for future revascularizations with only a numerical trend towards fewer non-fatal myocardial infarctions and no difference in mortality.
For HCC patients with HBV, atezolizumab plus bevacizumab provided a numerical trend toward better OS than most of the treatments and conferred a similar survival benefit when compared to other combination therapies ( Supplementary Fig. 18 ).
There was a numerical trend for the enrichment of responses in models with low tATM H scores by IHC for AZD6738 monotherapy (38% low vs. 0% high) but no differential for a combination where high tATM models showed >50% TGI responses (63% low vs. 67% high) but with the caveat of a low number of models.
There was a numerical trend for early separation between the spesolimab and placebo groups during the first week, favoring the spesolimab group.
Also, in a nearly 6000 patient trial in general ICU patients, the proportion of patients with a trauma diagnosis had a numerical trend toward benefit with the use of SDD [ 46 ].
However, there is a numerical trend suggesting a slightly higher occurrence of DE in the perioperative period in the Amulet group compared to Watchman group.
Higher infusion rates were associated with a numerical trend toward shorter T max , although a delayed T max was observed at the highest infusion rate (30 mg/kg cohort [7.5-min infusion duration; 4 mg/kg/min]).
A sub-analysis of the HOST-EXAM trial for complex PCI did not reveal any significant difference but only a numerical trend in favor of the clopidogrel group.
However, there was a numerical trend towards n − 1 subtask switch costs in the last subtask of noninterrupted trials and n − 2 subtask repetition costs in the last subtask of interrupted trials (1.62% vs. −0.77%; see Table 3 ).
Nevertheless, there was a numerical trend whereby processing speed was slower at side angles for two-handed symmetrical signs (see Fig. 7 b).
The only remarkable finding of these RT-qPCR results is that Prmt4/Carm1 loss reduces expression of Runx2 mRNA (at day 6, p < 0.001), with a numerical trend of decreased expression for Runx2 , Osterix/Sp7 and Dlx5 during the differentiation time-course (Fig.
There was a numerical trend towards longer ICU length of stay in surviving patients with hypothermia compared to patients with no hypothermia following ECMO decannulation (hypothermia: 22 (10–35) days vs. no hypothermia: 8 (5–20) days, p = 0.078).
There was a numerical trend toward fewer pest mites in the mass release compared with the control in this orchard ( Table S4 ).
Although LVMI was not statistically significant, there was a numerical trend, which is consistent with the results of unmatched analysis ( Supplementary Table S5 ).
21 , 24 Although there was a numerical trend in PFS favoring ibrutinib + CIT, the study was not adequately powered to allow for a formal statistical comparison, given the small number of patients with MZL.
They found a numerical trend in the opposite direction, i.e., the processing advantage for unpredictable words in constraining sentences compared to neutral sentences.
However, a numerical trend was observed for OS in favor of Isa‐Kd compared with Dara‐Rd after matching adjustment. 3.4.
We also observed enrichment of the peroxisome-proliferator-activated receptor alpha (PPARα) signaling pathway, along with a numerical trend of decreased AT levels of OEA and PEA, which are known to activate PPARα 68 .
Yet, owing to the small sample size solely a numerical trend and no statistical significance of the benefit of PMRT on the oncologic outcome of patients following a therapeutic mastectomy with remaining fibroglandular breast tissue could be shown.
There was a numerical trend towards a higher MACE rate with the monotherapy, which was predominantly driven by stroke events.
Yet, in our series, once PSM was adjusted by comorbidities, including age, sex, or pulmonary disease, the differences in mechanical ventilation disappeared although a numerical trend of non-apical forms was maintained.
There was also a numerical trend evident for the three groups independently (Table 2 ) with 5.13% versus 2.38% for severe CRS (relative risk 1.679; 95% CI 0.947–2.583), 5.77% versus 4.28% for severe CRS and NT (relative risk 1.247; 95% CI 0.6874–2.004), and 9.62% versus 5.94% for severe NT (relative risk 1.428; 95% CI 0.9038–2.085) although not reaching statistical significance.