Correlation of DTI metrics and cognitive output Low diffusivities showed a trend towards higher cognitive scores in many ROIs but in most cases, it did not reach statistical significance after correction of the p -value for multiple comparisons.
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Thus, although most analyses shown in 6B–E (derived from two biological replicates) did not reach statistical significance, there is a clear trend suggesting that the anti-proliferative activity of the low-dose combination results from either post-mitotic cell death or induction of post-mitotic cell cycle arrest or senescence.
Single timepoint weighing of honey supers (additional boxes provided for honey storage used as an approximation of honey production) further showed a trend toward increased weight in the P + LX3 group relative to P group at W12, although the difference did not reach statistical significance (33.30 ± 1.86 vs. 28.78 ± 2.82 kg/hive, two-tailed t -test, p = 0.2054; Fig. 1E ).
As said before, in the pineal gland ( Supplementary Table S4J ) phototransduction was also a highly significant pathway ( q- value = 0.006) while in the remaining brain regions it did not reach statistical significance. 3.5 Analysis of differential gene expression in pregnant and non-pregnant goats Samples from the pineal gland were not included in the differential expression analysis, since the removal of an outlier sample decreased the number of replicates from the pregnant group to two, which is insufficient to make a sound statistical analysis.
Therefore, we found that the mean weight of C643 xenograft tumors showed a trend toward increase compared to 8505C xenograft tumors; however, they did not reach statistical significance at the study endpoint ( Figure 2 B).
Actually, an increasing trend of KI67 gene expression was observed at 21-day, though this did not reach statistical significance.
Although there was a strong trend toward SR3 and SR5 predictive ability for grade 2+ chest wall pain, the optimal dosimetric parameters and thresholds did not reach statistical significance.
Compared with nonsurviving infants, surviving ILWH showed a trend for higher C5-specific binding activity measured by ELISA , although this difference did not reach statistical significance ( P = .07) ( Figure 2 A ).
The abundance of IL-6 also showed a trend of increase but did not reach statistical significance (Fig. 8 F).
In terms of anxiety rate, there was no discrepancy between groups at any assessment time points (all P > 0.05), however, anxiety rate showed a decreasing trend at M6 in CBSM group compared with UC group although it did not reach statistical significance (20.3 vs. 34.2%) ( P = 0.057) ( Figure 3A ).
Specifically, GEBR‐7b alone showed a trend towards an increase of pTAU‐S214 that, however, did not reach statistical significance in N2a cells.
However, while we observed a negative trend with PPP4C expression, the adjusted p value did not reach statistical significance using CIBERSORT ( online supplemental figure 7 ).
Treatment with AA and T3 showed a trend towards increased LDHB expression levels as compared to CTRL, but this did not reach statistical significance.
Conversely, a strong trend towards a negative correlation between NDEVs’ STX-1A/VAMP-2 concentrations and RBDSQ total score was also observed, although this correlation did not reach statistical significance.
Conversely, the PD-risk factor T408M (also known as T369M, rs75548401) showed a trend toward a faster rate of cognitive decline that did not reach statistical significance, in keeping with a previous study. 43 The mild GD-causing variant N409S (also known as N370S, rs76763715) has shown inconsistent association with cognitive decline in PD.
With the increase of wrinkles, there was an increasing trend of pH, but the difference did not reach statistical significance ( P >0.05).
Age showed a trend toward differentiation but did not reach statistical significance.
The experimental arm was associated with a favorable trend toward improved EFS versus RCT and placebo, but the difference did not reach statistical significance ( 20 ).
Notably, some clinicopathological factors showed a trend toward differences between molecular subtypes, although they did not reach statistical significance.
Quantification of tumor lesions at 26 weeks after Ad-Cre inhalation revealed that Rb1 FL/FL Tp53 FL/FL Rela FL/FL mice showed a trend toward reduced tumor presence compared to Rb1 FL/FL Tp53 FL/FL mice, which however did not reach statistical significance (Fig. 3C ).
Furthermore, a recent study elucidated variables associated with COVID-19 vaccination among Israeli adolescents (n=43,919) using data from an electronic database, showing that adolescents of low SEP had a very low vaccination rate (42.3%) compared to those having a high SEP (80.4%), which was highly significant upon univariate analysis but did not reach statistical significance using a multivariate approach [ 22 ].
In the complete case analysis, long shifts showed a trend toward increased sleep-aid use but did not reach statistical significance (OR 1.64, 95% CI 0.99–2.66) ( Data Supplement 3 ).
The 5-year disease-free survival showed a trend in favour of Textbook Outcome; however, this did not reach statistical significance (85% vs. 75%, p = 0.33) ( Figure 2 ). 4.
These levels showed a trend to be also decreased at week 12 in affected versus control mice ( Figure 1 b), although differences did not reach statistical significance.
IL-6 followed an increasing trend in both the treatment and control groups, with a mean difference of 674.6 ± 838.9 pg/mL in the treated and 341.3 ± 554.5 pg/mL in controls; however, this did not reach statistical significance ( p = 0.106 in treated and p = 0.552 in controls).