“did not reach statistical significance”

Unstimulated neurons expressing mGFP PICK1 and mCherry PICK1 showed a trend toward a shorter mGFP fluorescence lifetime compared to controls, which did not reach statistical significance, suggesting weak FRET between mGFP and mCherry in the PICK1 dimer under basal conditions.

Whereas rtTA-Kcnab1 mice showed a trend towards enhanced work after training, this change did not reach statistical significance, suggesting that the vascular Kvβ2:β1 ratio contributes to the training-induced improvement in exercise capacity in mice.

However, while we observed a negative trend with PPP4C expression, the adjusted p value did not reach statistical significance using CIBERSORT ( online supplemental figure 7 ).

Overall, most exons studied were significantly misspliced in adult DM1 brain samples, compared to non-DM controls: eight out of eleven exons were affected in frontal cortex ( ITGB4 exon 35 and MPDZ exon 28 showed a clear trend but did not reach statistical significance) (Fig. 9d ), whereas all exons studied were misspliced in the hippocampus of DM1 patients (Fig. 9e ).

While the 1 mg/L and 100 mg/L groups showed an increasing trend but did not reach statistical significance, the gata4 transcription levels peaked in the 10 mg/L groups, showing a 1.91-fold increase over the control group ( Figure 4 B).

There was a numerical trend suggesting a possible shift in breathing route from oronasal to nasal during both phases of the study (Table 3 ); however, statistical analysis of the data from the active phase by both Wilcoxon test ( P = 0.359) and two-sample t test ( P = 0.559) showed that this trend did not reach statistical significance.

The addition of pembrolizumab was associated with a favorable trend toward improved event-free survival versus placebo plus CRT, but the difference did not reach statistical significance in the ITT population (the 24-month event-free survival rate was 63.2% for the pembrolizumab arm versus 56.2% in the placebo arm). 62 Currently, several clinical trials are exploring the role of different ICIs in LACC setting ( Table 1 ).

Patients treated with Lantus showed a trend towards lower mean post-breakfast and pre-lunch BG levels compared with those receiving Basalin, although these differences did not reach statistical significance (Table 2 , Fig. 2 c).

This did not reach statistical significance (p=0.29, χ 2 1.117) but showed an important trend, given the rarity of moderate, severe or catastrophic adverse incidents.

Compared with nonsurviving infants, surviving ILWH showed a trend for higher C5-specific binding activity measured by ELISA , although this difference did not reach statistical significance ( P = .07) ( Figure 2 A ).

Our findings indicate that the total number of steps per day and the amount of vigorous activity showed a positive trend toward patients in remission, although this did not reach statistical significance.

Despite a strong trend towards greater timing adherence with dry powder capsules, the difference between the two study groups did not reach statistical significance.

While the secondary endpoints did not reach statistical significance, but showed a positive trend in favor of the ER2EP pathway ( Figure 2 ).

Other genes related to cell wall function, e.g., CH_4271 , also showed a trend of expression change similar to that seen in the triazole-resistant strains, but the data did not reach statistical significance ( Fig. 6c and data not shown).

The production of IL-1β, IL-12, and IL-17 was significantly decreased in the BALF but not in the lungs of Egr-1-deficient mice, which showed a trend of decrease but did not reach statistical significance.

In an early exploratory analysis of RTOG 9802, the subgroup of patients with oligodendrogliomas showed the greatest benefit statistically in terms of benefit from PCV whereas the astrocytoma subgroup only showed a trend (but did not reach statistical significance).

With respect to AIS grade conversion, there was a weak trend toward a higher rate of a 2-grade conversion among early surgery patients (risk ratio [RR] = 3.56, 95%CI 0.41-30.99) which did not reach statistical significance.

In contrast, despite having B cells detected ( Figure 3A ), comparable body weights (data not shown) and plasma lipids ( Figure S5 ), while atherosclerosis was an increasing trend with mice that received MHCII −/− and CD40 −/− B cells, it did not reach statistical significance ( Figure 3B ).

Analysis of LFS and OS in t(8; 21) AML With a median follow-up of 12.7 (range 1–44) months, the inv(16) cohort showed a trend towards superior LFS versus the t(8; 21) cohort, but it did not reach statistical significance ( P = 0.066).

Forskolin stimulation showed a trend to decrease p300 levels by 30%, which however did not reach statistical significance.

There was a slight trend for faster growth with GDNF at the later time point for UMSCC22B cells but the difference did not reach statistical significance.

With the increase of wrinkles, there was an increasing trend of pH, but the difference did not reach statistical significance ( P >0.05).

ODQ pretreated efferent arterioles also showed a trend towards increased sensitivity to runcaciguat as compared with L‐NAME pretreated efferent arterioles, but the difference did not reach statistical significance (Figure 3f ).

Consistent with the sequencing results, compared with non‐AF patients, two tsRNAs (tsRNA‐5006c‐LysCTT and tsRNA‐5030c‐GluCTC) were significantly upregulated in AF patients, and the remaining one showed an increasing trend but did not reach statistical significance.

26 - 28 There was an increasing trend in cervical lordosis in patients who underwent 2-level CDR, but the differences did not reach statistical significance, probably because of the limited sample size.