“nominally significant”

When only those 915 individuals possessing full data across all 10 environmental measures were analysed, the interactions between the 10-SNP-set and Teacher Negativity, Home Chaos and Parent Negativity were weaker, but remained nominally significant ( p < 0.05).

All loci identified here were directionally consistent, nominally significant with “rapid3” and/or “CKDi25” (one-sided P<0.05) and two were genome-wide significant for rapid3 or CKDi25 ( UMOD - PDILT , PRKAG2 - GALNTL5 ).

Fourteen out of twenty-eight selected SNPs showed nominally significant associations at p <0.05 with different dimension-specific quantitative assessments of psychotic experiences but each failed to meet statistical significance post correction for multiple testing ( p <0.0008; one-tailed).

If the MR analysis results were nominally significant ( P < 0.05), we considered that there might be a causal relationship between the intestinal flora and the lipids.

Exploratory pathway enrichment analyses based on nominally significant proteins ( p < 0.05) from the iciHHV‐6 proteomic models are summarized in Figure S2 (Supplementary materials 8 ) and detailed in Appendix V .

While the association was still nominally significant ( p < 0.05), it was no longer significant with the Benjamini–Hochberg procedure.

There was nominally significant evidence overall that the male ORs differed from those for ER-positive female disease (p = 0.05).

While on the whole, none of the cis -SNPs were genome-wide significant in the GWAS data, they were significantly enriched for nominally significant (p<0.05) SNPs in the BMI GWAS results ( [65] , binomial p = 0.007), indicating either their pleiotropic effect, or metabolic trait regulation through small RNA expression levels. rs2440129 was nominally significant in the BMI GWAS lookup [65] , while mir-195-3p was significantly associated with both rs2440129 in cis (FDR<5%, p<2.4×10 −5 ), as well as BMI (FDR<5%, p<3.9×10 −3 ) and PTFM (FDR<5%, p<4.1×10 −3 ), suggesting a mechanism for the rs2440129 association.

Of the 1,291 adult BMI variants compared, 395 variants (31%) were nominally significant ( p < 0.05) and 949 (74%) displayed directionally consistent associations with childhood BMI, which was far greater than would be expected by chance ( p < 0.001) ( Table S6 ).

A nominally significant association was observed for females with %AFR of ≥ 95% compared with those who had %AFR of 55.0–64.9% (OR: 1.42, 95% CI: 1.00–2.03, P = 0.05).

In all volcano plots and figure captions, metabolites surviving FDR correction (q < 0.05) are visually distinguished from those that are nominally significant only ( p < 0.05, uncorrected).

Signals at CALB2 , ZBTB10 and PRIMA1 showed nominally significant associations ( P < 0.05) with TV snacking, skipping breakfast and daily energy intake, respectively (Table 3 ).

Of the 13 assayed proteins, only 3 showed nominally significant difference (p<0.05) after the swimming experiment (CCL11, and CXCL10 lower and IL-1ra, higher).

The levels of all proteins (regardless of storage-time) with nominally significant ( p < 0.05) contributions were subsequently adjusted for age and/or plasma/serum by removing the contribution using the beta (β)-coefficient(s) from the linear models.

To identify metabolomic biomarkers independent of conventional risk factors including DKD, metabolites remaining nominally significant ( p <0.05) after further adjusting for CKD and severely increased albuminuria were assessed for the prognostic value.

Genes nominally significant in the MAGMA analyses ( P Bonf < P < 0.05) were meta-analysed using Stouffer’s method.

Resulting group-level oscillations were nominally significant (G-cosinor p < 0.05) in 5.9% to 85.8% of ROIs across seven of the nine MRI metrics (Supplementary Table 4 ).

Only the volumes of the caudate, corpus callosum and third ventricle achieved a heritability that was nominally significant in our sample (uncorrected P <0.05).

In addition, rs713998 showed a nominally significant ( P < 0.05) association with verbal memory, and this association did not remain after Bonferroni correction (verbal memory subtest score: A/A and A/G = −1.74 ± 1.28, G/G = −2.19 ± 1.31, β = 0.210, t = 2.704, permutation P value = 0.029).

Among these, 267 were nominally significant at p < 0.05, of which 87 related to FODMAPs, 71 to gluten and 109 to placebo, i.e. with no enrichment of associations to treatment groups vs placebo.

In females, we found a significantly higher proportion of CpGs showing increased variability with age among nominally significant ( p < 0.05) CpGs under inactivation, but not among CpGs escaping inactivation.

Clusters with nominally significant correlations ( p < 0.05; FDR corrected) were further analyzed with hierarchical regression models for descriptive analyses.

Causal effects were considered nominally significant (suggestive) when the IVW p < 0.05 and sensitivity analyses revealed no contradictory findings.

Eight of the 13 ALFRED genes with a nominally significant association between RDGVs and AI in at least one cancer type in the ALFRED analysis ( P < 0.05; Fig. 2d and Supplementary Data 5 ) also had an enrichment of RDGVs in a matched cancer type compared to in controls ( P < 0.05, Fig. 3d ; Supplementary Data 6 ): ATM in colon and rectum adenocarcinoma (COADREAD), lung adenocarcinoma (LUAD) and in PRAD, NSD1 in OV, and TPCN2 in uterine corpus endometrial carcinoma (UCEC).

We declare h g 2 >0 to be nominally significant (P<0.05) if h g 2 is larger than each value analogously estimated from 19 data sets with sample labels randomly permuted (thus, 5% of genes will be nominally significant even in the absence of a true effect).