The MHC-I protein level showed a trend to downregulation, and the mRNA level was significantly decreased.
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A subgroup analysis according to age (75–85 years [n=148] and >85 years [n=38]) showed a trend toward greater improvements in pain control and bowel function in the subgroup aged >85 years ( Figure 4 ).
Using the suggested 3 genes from BestKeeper showed a trend to higher levels of TFB1M in BA 8 from subjects with schizophrenia (Fig. 5d ), NormFinder did not reveal any significant variation with diagnoses in that cortical region (Fig. 5g ) whilst using reference genes suggested by geNorm showed a strong trend to lower levels of NOL9 in subjects with schizophrenia (Fig. 5j ).
Of the protein C SNPs analyzed, the AA genotype of the rs1799810 SNP showed a trend toward increased mortality (26 % vs. 19 %) compared with the TT/AT genotypes, but this trend was not statistically significant ( p = 0.18).
Intraperitoneal insulin tolerance test performed at 12 weeks of age showed a trend toward increased insulin sensitivity in male ( Fig. 3 G ), but not female ( Fig. 3 H ), ΔF508 homo- and heterozygous mutant mice.
Treated mice also showed a trend of reduction of ParaThyroid Hormone (PTH) ( Figure 3f ), decrease of osteoclast number over bone perimeter and osteoclast surface over bone surface ( Figure 3g – i ), and reduction of mRNA expression of osteoclast-specific genes ( Figure 3j ), which are in agreement with the reduced serum levels of TRAcP ( Figure 2d ).
There were no significant differences between WT and PD-1KO mice although the latter group showed a trend for fewer antibody-secreting LLPC ( Fig. 1c ).
Electrocardiogram showed a trend toward increased QT intervals at 90 mg/kg/day groups.
In the current study, wild-type fibroblasts showed a trend towards decrease in the maximal OCR within 30 min of 1 mM PQ treatment which was preserved in the Surf1 −/− fibroblast. t -BuOOH and H 2 O 2 did not result in any changes in basal OCR, maximal respiration, or reserve capacity.
To inflammatory parameters, we observed a reduction of 8.3% in the levels of CRP (from 3.0±2.2 to 2.2±1.3; p=0.07) and of 17.4% in IL-8 (from 84.8±55.5 to 48.8±18.8; p=0.058), both showed a trend toward statistical significance.
Levels of MFN1 showed a trend toward an increase in vehicle-treated gp120 tg mice compared to non-tg mice (Fig. 6a , d ), and treatment with FK506 significantly increased levels of MFN1 in gp120 tg mice (Fig. 6a , d ). mtHSP70 was detected as a single band at approximately 72 kDa (Fig. 6a ).
Cirrhotic livers showed a trend of increased incidence compared with minimal fibrosis or perisinusoidal/pericellular fibrosis, though not statistically significant ( P = 0.05235 or P = 0.20697, resp.). 3.4.
This study also showed a trend towards poor survival in patients who were treated with immunosuppressants, especially intravenous high-dose cyclophosphamide.
JAK3 inhibition showed a trend toward reducing all the evaluated Th1 cytokines, but it is noteworthy that there were significant reductions in the secretion of TNF-α, IFN-α, and IL-17.
During the entire period of 1982–2012, many high-latitude regions showed a trend towards earlier BGS and delayer EGS, resulting in a longer LGS, but trends in PGS show a more fragmented pattern than BGS, EGS and LGS.
There were no evidence of heterogeneity among the studies (p= 0.860, χ 2 = 2.57, I 2 =0.0%). Four trials showed a trend towards a reduction in EDSS score during the IVIG treatment when compared to the baseline.
There was a trend toward hyperconnectivity among alpha sources located in sensorimotor cortex, while an alpha source in the cerebellum showed a trend of hypoconnectivity to multiple regions in the parietal and temporal lobes.
Factors such as publishing in non-chiropractic journals showed a trend towards improved quality of reporting scores, although this was not statistically significant in the multivariate regression analysis.
Blue-yellow CSFs showed a trend similar to red-green CSF up to 4 cpd, but at higher spatial frequencies (6 and 8 cpd) there were signs of luminance intrusion to chromatic aberration ( Figure 3B ).
Additionally, while the control flies showed a trend of reduced parasite load over the course of 12 days of infection, the flies defective in phagocytosis had a parasite load that increased over three days post-infection and remained elevated until day 12 ( Fig 2D ).
An unexpected finding of the present study was that patients with sigmoid cancer showed a trend of improvement of the estimated disease-free survival and overall survival compared with cancers of the upper-third rectum.
These mice showed a trend to decreased L-NAME-induced endothelium-dependent constriction ( Figure 3 F ).
Levels of Mmp2 and Ptk2 showed a trend towards higher levels in OP, but differences were only significant at the level of intra-individual comparison to non-remodeled lung tissue in CCL2 transgenic mice.
The patients tested on the binocular rivalry task showed a pattern of percept duration distributions that was similar to their performance on the SFM task ( figure 5 c ), and the mean percept durations for all three bistable stimuli showed a trend towards being correlated with each other, although this did not reach statistical significance (rotating sphere-binocular rivalry, r = 0.61; rotating sphere-dot quartet, r = 0.13; figure 5 d ).
One small cluster in the left caudate tail showed a trend toward a significant interaction ( p corrected > .06; [TAL XYZ = -26–46 4] 906 mm 3 ).