Barely Significant

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a clear trendp = 0.091.8× alphagold
Changes in CTC-cluster counts from baseline to follow up were not able to predict patient outcome in terms of PFS and OS, however, for patients in the high risk group, there was a clear trend towards a shorter OS ( P log-rank = 0.07) and increased risk of death, with a HR of 2.96 (95% CI 0.83–10.5; p = 0.09) ( Figure 4 , Table 4 ). 2.6.
showed a trendp = 0.0931.9× alpha
The tumor patients group only showed a trend for the main effect tumor volume (F(1;10) = 3.5; p = 0.093 n.s.; d = 1.18) and a significant interaction effect of eccentricity × tumor volume (F(2;20) = 5.1; p = 0.016; d = 1.43), while, in the lesion patients group, we only found a significant main effect of the factor area (F(2;10) = 4.8; p = 0.034; d = 1.96).
marginally significantp = 0.0971.9× alphagold
0.0036, p = 0.037; Table 1 ); a marginally significant difference also occurred in GCs with or without lymph node metastasis (0.0025 vs. 0.0013, p = 0.097; Table 1 ); and a difference in the P16 methylation level in SMs was found between poorly and well/moderately differentiated patients (0.0021 vs. 0.0013, p = 0.018; Table 2 ).