Barely Significant

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As for the parallel (co)morbidity clusters in COPD and controls, telomere length was comparable between both “Less (Co)morbidity” clusters C1 and X1, and significantly reduced in cluster C2 versus X2, while the difference failed to reach statistical significance for cluster C3 versus X3 (10.22 ± 1.90 versus 10.82 ± 1.45 kbp, p = 0.05) ( Figure 5 and Appendix A , Table A2 ). 4.
borderline significantp = 0.051.0× alphagold
This protective effect was particularly pronounced in patients with HFrEF, where OMT compliance was associated with a 38% risk reduction compared with no OMT (HR 0.62, 95% CI 0.39–0.98, p = 0.04), and showed a borderline significant association in HFpEF (HR 0.58, 95% CI 0.34–1.00, p = 0.05), but not in HFmrEF (HR 0.65, 95% CI 0.36–1.15, p = 0.14).
However, HDL cholesterol (OR = 2.511, 95% CI: 0.992–6.358, p = 0.052), systolic blood pressure (OR = 0.490, 95% CI: 0.227–1.058, p = 0.069), diastolic blood pressure (OR = 0.445, 95% CI: 0.177–1.118, p = 0.085), and fasting glucose (OR = 1.985, 95% CI: 0.449–8.771, p = 0.366) did not reach statistical significance at p < 0.05, indicating the limited predictive power for WHR in this model.
a favorable trendp = 0.0501.0× alphagold
borderline significancep = 0.0501.0× alpha
However, willingness to reuse the catheter system showed a favorable trend in Group 2, reaching borderline significance in a pairwise comparison with the control group ( p = 0.050) ( Figure 3 ).
highly significantp < 0.051.0× alphaqualifiedgold
Influences on vTUG Total Time Among the tested variables, the UPDRS III gait subscore, patient-reported motion status, shoe type, and chair used significantly improved the AIC, reducing it from 998.19 in the base model to 938.57 in the full model, and were highly significant in the likelihood ratio test (LRT) ( p < 0.05).
borderline significancep = 0.051.0× alpha
Beyond the top eight protein networks influenced by SARS/MERS infection, our analysis shows that Transmembrane Serine Protease 2 (TMPRSS2), a protein recently proven fundamental for SARS-CoV-2 entry in the cell [ 64 ], interacts with the viral Spike protein S ( Figure 1 ), and it is downregulated by beta-coronavirus infection ( Figure 3 ), although at borderline significance and not amongst the top eight ( p = 0.05, Table S2 ).
borderline significancep = 0.051.0× alpha
Subgroup Analysis When stratified into subgroups, time to intubation was shorter for thermal-softened ETTs than for room-temperature tubes in the SLTs with borderline significance (MD: −15.82, 95% CI −31.52 to −0.12, p = 0.05), and were significantly longer in DLTs (MD:1.78, 95% CI: 0.27 to 3.30, p = 0.02) ( Figure 8 ).
a trend toward significancep = 0.051.0× alpha
In the unadjusted model, higher MDS-OAβ levels were significantly associated with a lower TBR in the frontal (β = −0.04, p = 0.02), central (β = −0.06, p = 0.02), and temporal lobes (β = −0.06, p = 0.01), with a trend toward significance in the parietal lobe (β = −0.05, p = 0.05).
For the KOOS Activities of Daily Living domain, the intraosseous PRGF group also demonstrated significantly better results at 6 months ( p = 0.007) and 12 months ( p = 0.002), though the difference at 3 months did not reach statistical significance ( p = 0.050). 3.3.