Excerpts

Regarding conditional features, although their average feature importance was modest, certain key features, such as TP53 mutation, growth rate, and tissue of hematopoietic and lymphoid origin emerged as highly significant, even when compared with other omic datasets (Fig. 4a , Supplementary Data 9 ).

For both frequency (F 2,130 = 4.03, p = 0.02) and size (F 2,130 = 3.08, p = 0.05), there is significant slope heterogeneity, but the regressions for individual components (π AA , π DD and π AD ) are only marginally significant or non-significant.

44 found an intensity drop in proton radiation belts from 2010 to 2012 while maintaining an increasing trend during the rest of the Cassini mission.

Increasing ambient temperatures leads to a negative trend in the heating demand, while for cooling demand, it is the opposite 33 .

This has led to a positive trend in the historical generation.

Since the sensorimotor network showed a trend towards significance, we performed a post-hoc analysis to investigate which parts of this network drove the effect.

As salt concentration increased, the cis -cleavage efficiency of all Cas12 orthologs exhibited a decreasing trend (Fig. 2e and Supplementary Fig. 6b ).

Even though these results did not withstand a correction of multiple comparison, a clear trend was visible.

Only 2.9% of the patients receiving anti-CTLA4 treatment post-LAD developed lymphedema, indicating a highly significant effect of anti-CTLA4 monotherapy in preventing lymphedema.

There was a highly significant enrichment of Cluster 0-like cells in the previously designated IL1β + cluster (4682 Cluster 0-like cells/7985 IL1β cells) compared to the rest of the dataset (1102 Cluster 0-like cells/52,706 Other cells, χ2 = 25707.926 p < 0.0001, Chi-squared test with Yates correction).

On day12, collagen deposition in the JHA group no longer increased and showed a decreasing trend which prevent excessive inflammation for reducing scarring, while the POF-only group and Iodoform group showed continuous increase, indicating that inflammation delayed the healing time, stimulated scar formation, and slowed down the wound repair process.

An interesting trend was observed between the specific surface areas of TiN synthesized at different ammonia treatment temperatures and their responses to NO 2 : the sensor response was proportional to the specific surface area (Table S4 ).

We report that eWAT from mice with endothelial IGF-1R knockdown had a strong trend for reduced basal levels of lipolysis compared to control mice and had a significantly higher lipolytic capacity.

We also observed a significant decreasing trend in SNAIL expression and an increasing trend in the expression of the SNAIL target genes OCLN , DSP and CLDN9 after L3MBTL3 was knocked out in MDA-MB-231 and SUM159PT cells (Fig. 5f ).

The D 2 band, on the other hand, does not show a clear trend, with the Raman shift scattering for films with high strain.

We found that CPT1 activity showed a trend of being higher in mitochondria isolated from SOD1 G93A brains at symptomatic stages, contrary to SPC, which showed no significant changes compared to controls (Fig. 3g ).

This showed a trend to lower peak VL at higher levels of CCR5 gene disruption and an increasing number of uninfected animals at high gene disruption.

A decreasing trend of Li content with increasing distance from the contact can be ascribed to either fluid metasomatism 31 or the migration of Li by diffusion 12 , 13 , 32 , 33 .

More importantly, both Li contents (decreasing from 974 to 239 ppm) and Li isotopic compositions (δ 7 Li decreasing from +1.5‰ to −13.8‰) show a clear trend of change with increasing distance from the pegmatite–country-rock contact (Fig. 3 b, d ).

63 – 67 ) and there is an overall trend that the anions with higher ED strength cause larger shifts for the protons of 1 .

Furthermore, compared with SSCVs identified by juncmut, the variant chosen by SpliceAI 23 , a machine learning-based splicing effect predictor, showed modest significance (Fig. 1e , see “Methods” section for details).

In our study, DEX treatment in models of asthmatic mothers showed a trend towards increased ILC2s in the lungs of the offspring, suggesting that maternal glucocorticoid use in asthmatic mothers may enhance ILC2 function in the offspring and increase their risk of asthma.

This led to an overall trend of the KE toward its stable state during the past decades, given the more unstable KE during the 1980s and 1990s due to the positive PDO phase (Supplementary Fig. 7 ).

The density of products follows a decreasing trend (Fig. 5d ), indicating the reactions extended the carbon chain length while introducing substantial amounts of oxygen-containing groups.

Comparing egg numbers between Dmel and Dbus revealed highly significant differences for several substrates (Fig. 1b ), indicating a distinct shift in preferred oviposition substrates between the two species.