Excerpts

The [S]-rHDL group showed a trend towards a decrease of 17% compared to the oral statin group (Mann-Whitney U test p=0.06, Fig. 4c ).

Additionally, the LR group showed a strong trend towards less T cell proliferation ( p = 0.06) and significantly less proliferation of B cells ( p < 0.01, Fig. 5E ).

An analysis of variance revealed differences in the proportion of cells in S-phase, G2/M-phase and G0/G1 in Shh creERT2/C mutant versus Shh +/C littermates that approached significance (F (2,8) =4; P =0.06).

QPCR assays showed reduced expression of Ccr2 and its ligands Ccl2 , Ccl8 and Ccl12 in muscles of CD11b/LIF BMT recipients, and a strong trend for lower levels of Ccl7 expression ( P = 0.06) (Fig. 4a ).

The variant rs150665432 showed a significant trend ( P = 0.06) in the much smaller replication dataset.

Combining these regions into a meta-ROI, we observed that the AD+LB+ group exhibited faster glucose hypometabolism than the AD+LB− group at a statistical trend level ( p = 0.06, Fig. 3C ).

Mutant frontal OFs showed a trend of greater area compared to WT (2053 ± 411 μm 2 , n = 6, compared to 1562 ± 381 μm 2 , n = 6, p = 0.06), and mutant parietal OFs had a significantly greater area compared to WT (1773 ± 281 μm 2 , n = 6, compared to 1231 ± 355 μm 2 , n = 6, p = 0.02).

Notably, patients achieving CR exhibited markedly higher T cell activation immune scores post-treatment compared to those PR patients, demonstrated by a trend toward significance ( P = 0.06, Fig. 5c ).

RT-qPCR confirmed induction of NOTCH/TGF‐β‐pathway genes ( NOTCH1 , HES1 , TGFB2 , TGFBR2 , and ID3 ) and reduction of ASCL1 and DLL3 , with some markers showing borderline significance (e.g., TGFBR2 P = 0.06) (Fig. 9j and Supplementary Fig. 18h, l ).

12g ), with Panc 05.04 cells showing a nonsignificant trend in the same direction (1.12 fold, P =0.06; t-test; Supplementary Fig. 12g ).

Post hoc comparisons showed that double word-color incongruency significantly slowed down target response only when the target was not a Stroop word (paired t(19) = −2.43, p = 0.02, marginally significant after correction), but not when it was a Stroop word (paired t(19) = −1.96, p = 0.06) (Fig. 2a, b ).

The quantification results revealed a statistically significant positive correlation between TET1 and GCLC protein levels (Pearson r = 0.705, P < 0.001), and a positive trend was observed between TET1 and GCH1 expression (Pearson r = 0.331, P = 0.060).

The results for females were marginally significant for all villages ( N =126, r =−0.14, Student’s t -test P =0.06) and inland villages ( N =29, r =−0.27, Student’s t -test P =0.08), but not for coastal villages ( N =97, r =−0.1, Student’s t -test P =0.14).

When we remove White 20, one of two birds with the fewest numbers ( N = 3) of HVC X recorded, all but one of the remaining birds considered individually had P values < 0.001 (16 birds), with the remaining one marginally significant ( P < 0.06), and with the group data yielding values of R = –0.75 and P < 10 −4 .

Total developmental time from egg to adult emergence ranged between 23 and 31 days and was shorter on smaller hosts (ANCOVA: F 1,109 =8.11, P <0.005, r 2 =0.05, n =112) and shorter in broods developing from larger numbers of eggs (ANCOVA: F 1,109 =32.48, P <0.001, r 2 =0.22, n =112); the interaction between these main effects was marginally nonsignificant (ANCOVA: F 1,108 =3.62, P =0.060, n =112).

Furthermore, a statistical trend in the interaction effect was also found F(2, 26) = 3.15, p = 0.06 in which post-hoc comparisons revealed that only in the opsin condition animals at phase 20 cm kept significantly increased defensive distances compared to phase 10 cm as well as to phase none ( p < 0.05 and p < 0.001) respectably, while no differences were found within the control group.

Interestingly, NOD mice treated with BIBO3304 displayed a significant decrease in glucose levels (Placebo, 5.35 ± 0.11 mM; BIBO3304, 5.03 ± 0.09 mM; * P < 0.05), which is associated with a strong trend to increased insulin levels (Placebo, 73.31 ± 9.42 pM; BIBO3304, 103.2 ± 11.87 pM; P = 0.06), indicating that β-cells in a T1D environment are responsive to the inhibition of Y1 receptor signaling.

We found that the presence of Ssk-FB4s was always associated with stronger resistance against viral, bacterial and fungal infection in all datasets 71 – 73 : the comparison reaches marginal significance in one set with female flies subjected to bacterial infection ( P = 0.06, Supplementary Fig. 19 ), and significance in another two sets with flies subjected to fungal infection ( P = 0.002 and P = 0.02, respectively).

During the reward delivery event, the cOFC did not exhibit a significant trend (t(4) = − 0.29, p = 0.78), but the pACC exhibited a marginally significant effect (t(4) = − 2.55, p = 0.06).

The meta-analysis of the FUT2–ABO interaction effect in the discovery stage revealed a borderline significant interaction (OR = 1.08 (95% CI = 0.99–1.17), P = 0.06), with significant evidence of heterogeneity between the two discovery studies (heterogeneity P = 0.002).

Comparison among correlation coefficients showed a nearly significant difference between rapamycin and placebo arm in serum NfL ( p = 0.0608); the difference was less pronounced for pNfH ( p = 0.1429).

The high PSPI1 H-score approached significance ( p = 0.061) in the matched TMA-internal but not in the TMA-validation TMA ( p = 0.36).

Reco BM was on average 13±4% larger than Reco EC (marginally significant at P =0.061).

Among the top-ranked genes identified in the discovery stage, marginally significant associations were observed for MYO5B ( P = 0.061, promoter/enhancer) and AUTS2 ( P = 0.089, synonymous) in the replication stage.

The median and interquartile range (IQR) for blood collection from severe (5 [IQR 4–7] days) versus mild-moderate groups (4 [IQR 2–6] days) approached significance ( t -test p = 0.061).