Barely Significant

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The number of mitochondrial cristae in MC3T3-E1 cells in the ADI group was clearly significantly reduced, and even mitochondrial fragmentation occurred, which was slightly rescued in the CZ or CZ@LC groups, whereas the number of mitochondrial cristae (yellow arrow) was rescued in the CZP or CZP@LC groups due to robust inhibition of lipid synthesis (Fig. 8I ).
While an overall trend of increasing median elevation with proximity to volcanoes is present for all search radii, the stronger signal is found within the first 5 km.
Volcanoes stunt nearby glaciers.
Nat Commun · 2025 · PMC12397297
highly significantqualifiedgold
Furthermore, in DKD patients at different stages, there is a positive correlation between kidney lipid droplets and the albumin excretion rate (AER) 15 ; a highly significant correlation between the increased expression of lipogenic genes, including LDLR, CD36 and SCD1, and the progression of human DKD and a decrease in the eGFR; and a highly significant negative correlation between the expression of fatty acid oxidation genes, including PPARα and CPT1, and the eGFR 13 .
In internal replication, all the newly identified loci were nominally significant both in East Asian and European populations (Supplementary Fig. 7b and Supplementary Data 25 ). rs35593046 ( CACNA1D ), rs7659823 ( EDNRA ), rs5823966 ( ZNF397 ), and rs1541596 ( CARM1 ) were much more frequently observed in the East Asian population (Supplementary Fig. 7c and Supplementary Data 25 ).