Excerpts

Cerebellar lesions were more commonly found in the OCB-positive group, which demonstrated a trend towards significance (24% vs. 3%, p = 0.023 and 0.057 before and after adjusting for disease duration).

HDAC5 mRNA expression in classic monocytes of MD patients showed a trend towards an increase compared to HC ( p = 0.023; FDR correction q = 0.092) (Fig. 5 A).

The OR (95% CI) for periodontitis were 1.09 (0.99–1.19) in working group of 40< and ≥52 and 1.10 (1.01–1.20) in working group of >52 hours per week with a significant trend (p = 0.0233) even after adjusting for age, socioeconomic status, healthy behaviour, chronic disease, and dental care status.

Although the correlation coefficient between serum PG I/II ratio and HOMA2%B did not reach statistical significance, the partial correlation test confirmed this negative relationship after adjusting for age and gender (partial correlation coefficient r = −0.0778, p = 0.0233).

A significant decrease in RBD + B cells was observed when BTKi grouped patients (median = 0.12 per 10 6 lymphocytes) and treatment naïve (median = 41.8 per 10 6 lymphocytes) patients, that approached significance ( p = 0.0238) (Fig. 4 B).

Results Changes at community and guild levels In general, species richness in local communities was lower in 2016 than in 1990/1991, although the difference was not quite significant when controlling for multiple comparisons (Fig. 1a ; Wilcoxon signed-rank test, Z = −2.263, p = 0.024; the critical p - value using the B-Y method is p = 0.0219).

the GA or GA+AA phenotype but the differences did not reach statistical significance after multiplicity adjustment (42.6% vs. 27.6%, p = 0.024; 42.6% vs. 27.4%, p = 0.015).

4 , right panel); (b) for HLA-I, there was a marginally significant effect of Gene (P = 0.024, F-test), with higher PBA values for gene C (Fig. 5 A), whereas the Virus × Gene effect was not statistically significant (P = 0.166, Greenhouse–Geisser test) (Fig. 5 B); (c) For HLA-II, there was a significant effect of Gene (P = 0.011, F-test), with higher PBA values for gene DQB1 (Fig. 6 A), and the Virus × Gene effect was highly significant (P < 0.001, Greenhouse–Geisser test) (Fig. 6 B).

Within the allergic diseases and moderate-to-severe asthma gene-sets, FLG was nominally significant in the loss-of-function burden test (P = 0.024, OR = 1.473), and eight additional genes passed nominal significance in the high or moderate (PolyPhen > 0.5) impact burden test ( RERE, IQCB1, PPP2R3C, PITPNM2, DYNAP, TSLP, EAF2, RASA2) (Supplemental Tables S9 and S10 ).

The T allele of TLR3 (rs3775291) SNP in a recessive model (TT) also showed a clear trend to increase the risk of the outcome (nominal P value = 0.024).

Intermediate chronotypes also scored better than evening chronotypes although the difference did not reach statistical significance ( p = 0.024, Cohen’s d = 0.22) (Fig. 1 ).

Similar to the comparison between binge drinkers and non-binge drinkers, a nominally significant genetic effect was identified for maternal variant rs869978 for binge drinkers versus non-drinkers (p = 0.0242).

While insect numbers on the Mp_C002_dsRNA plants did not differ significantly from that on the empty vector control plants in either generation, the BestBet plants did show a reduction in aphid numbers at a marginal significance level in the second generation (p = 0.025; Fig. 3b ).

Further, we ensured that the mean values across electrodes submitted to a paired samples t -test for each animal were significant or were at least a statistical trend for each animal, adjusted for multiple comparisons (pitch and rule tests for each animal; corrected p value = 0.025).

In multivariable logistic regression analysis including geographic variables only, variable “[number of] Distinct states” was strongly associated with higher odds of success (OR = 1.04, p = 4.57e-36), while trials conducted in more rural settings had lower odds of success with slight significance (OR = 0.86, p = 0.025) as shown in Supplementary Table S6.

As seen, the deficits in FFM and FFMI among children included by WLZ-O compared to MUAC-O were greater among stunted compared to non-stunted children, although only marginally significant for the FFMI (interactions non-stunted children vs stunted children and admission criteria with respect to FFM, p = 0.025, and FFMI, p = 0.078).

meQTL analysis After meta-analysis, a SNP (rs2611513) mapped to PRKG1 was nominally significant in association with methylation patterns of cg17426237 at PARG ( n = 141, p = 0.025; Fig. 4A ).

We found nominally significant polygenic enrichment of associations with college completion (p = 0.025), educational attainment (p = 0.043) and general cognitive ability (p = 0.015 and 0.025, respectively), suggesting that variants influencing these phenotypes are more prevalent in evolutionarily salient regions.

The exceptions are the measures of the fourth internode, and overall stem length that are borderline significant ( p = 0.0254 , and p = 0.0068 , accordingly).

Regression analysis showed that there was no significant change of CRO incidence in monthly trend in control group (p = 0.3556), but CRO incidence showed a decreasing trend in active surveillance group (p = 0.0256) (Fig. 2 ).

In addition, a small effect with marginal significance ( P = 0.0259) was observed for NP in 2011, in which the enhancing allele was derived from MY46.

IgM achieved a borderline significance in the overall comparison and further pairwise comparisons showed that IgM protein levels demonstrated a significant increase in AD V (p = 0.026) and AD VI (p = 0.029) compared to Normal.

Further analysis of the univariate analysis results shows that patients with Tx stage already exhibited an increasing trend in reintubation risk in the univariate analysis (OR = 8.81, 95% CI: 1.30-59.72, p = .026), and this trend remained statistically significant after multivariate adjustment.

The energy and frequency range only exhibited borderline significance (p = 0.026, Fig. 5G ; p = 0.01, Fig. 5I respectively).

Within season pairwise comparisons between exclosures and controls were not significant after adjusting α for multiple comparisons (α = 0.013); however, fall growth rates of males in exclosures (0.23 ± 0.05 g/day) compared to controls (0.08 ± 0.05 g/day) approached significance ( t = −2.24, d.f . = 288, P = 0.026).