Barely Significant

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a statistical trendp = 0.051.0× alphagold
In the univariate analysis, smaller FCD volumes showed a statistical trend of being correlated with higher AI values after controlling for age at MRI (Spearman’s correlation: − 0.48, p = 0.05, Fig. 2 B), whereas other epilepsy-related or lesion-related features were not related to AI values (Table 4 ).
nominally significantp < 0.051.0× alphagold
We checked statistical assumptions of nominally significant ( p < 0.05) linear regression models (Parts 2 and 6) by means of visual inspection of the following residual plots: correct specification of the model (residuals vs. fitted values), normality of residuals (normal Q–Q), homoscedasticity of residuals (scale location) and existence of outliers or influential data points (residuals vs. leverage).
marginally significantP = 0.051.0× alphagold
In non-diabetic participants (n = 8610), though the associations of the two GRSs with the four lipids were weakened, the results of causal association analyses were consistent with the analyses in the whole study sample, except for TC which was marginally significant in analysis with the Conservative GRS ( P = 0.05) (Supplemental Table 6 ).