Barely Significant

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Thereafter, although the gravel beach is periodically affected by tidal action with fresh inputs of spilled oil, the residue oils, depending on the time sequence, exhibited full depletion of n -alkanes, a decreasing trend for isoprenoids, and no discernible changes in saturated biomarker distributions ( e . g ., steranes, hopanes; Supplementary Fig.
The cell spreading area quantified from the F-actin staining showed an increasing trend as the substrate stiffness increased (Fig. 1D ), in that the average cell spread area was <1000 μm 2 on the softest micropillars (0.012 nN/μm) but >2000 μm 2 on the stiffest micropillars (1.014 nN/μm).
In general, after controlling for all available confounders, we observed a slight but significant increase in the risk of having a cancer diagnosis for subjects under either a medium or high level of stress, compared to the reference group (‘low stress level’), with multivariable adjusted HRs of 1.04 (95% CI 1.01–1.09) for the medium stress level group and 1.06 (95% CI 1.00–1.11) for the high stress group, showing a clear trend to increase (Table 2 , p for trend = 0.048).
To obtain a clear trend of the evolution of the three phases identified here as the discharge of sulfur-CuS hybrid electrode progresses, the peak area of three relatively strong reflections S (222), CuS (103), and Li 2 S (111) were chosen to be integrated at each depth of discharge and plotted together against discharge capacity in Fig. 2B .
Comparison of the multidecadal SST variability in both records shows a highly significant positive correlation for the period after the MCA (1230–1900 AD) (R = 0.29; P = 0.03) when compared to randomly generated red-noise data, and a positive correlation for the period 300–900 AD (R = 0.42; P = 0.12), although only marginally significant, which is probably due to the low data-resolution in core MD99–2322 (see supplementary information for statistical analysis).