Excerpts

Under the low ionic strength condition, after 63 days, differences between untreated and sodium periodate-treated saliva samples appeared at the limit of significance (paired sample t -test, p < 0.0021).

Calcifications vary by pathological stage Both lattice parameters (‘a’ and ‘c’ axes) for HAP showed a decreasing trend with increasing pathological stage, with a significant weak negative correlation between the ‘c’ axis and pathological stage (r τ = − 0.284, p = 2.17 × 10 –3 ) (Fig. 4 a,b).

In control pups, separated for 15 minutes per day, gamma power had highly significant correlations with both age (p = 0.0022) and weight (p = 0.0024); gamma in pups separated for 180 minutes per day was not correlated with either factor.

The linear correlation of the in vivo and in vitro measures from brains with both procedures was highly significant (R 2 = 0.709, P = 0.0023; Fig. 3F ).

Conditioning on this common variant rs3817928, the joint test of gene-by-current-smoking analysis for GPR126 remained nominally significant in the discovery ( p -value = 2.4E−03) and genome-wide significant in the replication studies ( p -value = 3.9E−09 in UK BiLEVE and p -value = 9.6E−17 in UK Biobank, Table 3 ).

Statistical analysis revealed the following: channel diameter measurements gave highly significant difference when comparing white-blue (p = 0.0025), white-green (p = 0.0033), blue-red (p = 0.0001) and green-red (p = 0.0001) but no significant difference between white-red (p = 0.0586) and blue-green (p = 0.8017).

Using ANOVA, association of the three factors was highly significant (IL37 SNP (p = 0.0026); M2 (p = 0.0027); M6 (p = 0.0023)).

The interaction between time and treatment effects on urinary free FB 1 was linear and highly significant (p = 0.0027 in the low-dose group and p = 0.0006 in the high-dose group).

Response When the 57 EGFR -mutant NSCLC patients of the training cohort were grouped as erlotinib responders and non-responders according to BIM mRNA expression, a clear trend emerged: 88.9% of patients with high BIM mRNA expression responded to erlotinib vs 22.2% of patients with low/intermediate BIM levels ( P = 0.0027).

PRRX1 exhibited one highly significant correlation with TMEM33 ( r = − 1.000, p = 0.0028), while SLAIN2 showed significant positive correlations with PTPN2 ( r = 0.886, p = 0.033) and TMEM33 ( r = 0.943, p = 0.017).

In the RNA-Seq data, TET3 showed a trend for differential expression in the SGA placentas (DESeq: P = 0.0029; DESeq2: P = 0.00035).

Notably, a significant trend was observed across the different CAR categories ( P = 0.003; Table 2 ).

The SAFT90 protocol showed borderline significance (pre: 7.46 ± 1.55, post: 6.53 ± 1.36; Z = 2.941, raw p = 0.003, ES = 0.50) (Fig. 7 C).

As shown in Table 2 , high WTAP expression was identified in 44.7% (84/188) of cases with tumors larger than 2 cm and in 28.9% (46/159) of tumors ≤ 2 cm; the between-group difference was highly significant ( P = 0.003).

Moreover, accounting for effects explainable by those on generic psychopathology reduced the magnitude of the pre- and postnatal anxiety by stroking interaction effect on irritability by just 12%, and with improved precision this interaction effect on irritability remained clearly significant (p = 0.003).

The female had no significant effect (F 1,79 = 2.34, p = 0.130), but there was a highly significant effect of the male × female interaction (F 1,79 = 9.52, p = 0.003), because interspecific matings were shorter.

For HbA1c levels, no significant differences were observed among obesity groups in the baseline, but HbA1c levels had an increasing trend (p-value = 0.003 in linear trend) and show significant differences in the follow-up (SI Fig.

Our data on the decrease of BMI are important and highly significant (p = 0.003).

Correlations between saliva cotinine levels and number of cartridges/day were highly significant for study groups A and B (Rho = 0.93 for group A, p = 0.003; Rho = 0.95 for group B, p = 0.0004).

S1 ) and even succeeded in replicating the nominally significant difference between NG and IFG groups in has-let-7a levels (p = 0.003, FC = 0.97) and the borderline significant result in hsa-miR-144-5p levels (p = 0.061, FC = 0.91) in the same setting.

Comparative analyses of functional connectivity strength within the four regions of interest (ROIs) and among the six ROI pairs in the two athlete groups demonstrated highly significant differences in correlation coefficients for PFC-L ( P = 0.003, Hedges’ g = 1.48, 95% CI[0.74, 2.22]), PFC-R ( P = 0.003, Hedges’ g = 1.49, 95% CI[0.75, 2.23]), M1-R ( P = 0.003, Hedges’ g=−1.34, 95% CI[−2.07, −0.61]), PFC-L-PFC-R ( P = 0.004, Hedges’ g = 1.50, 95% CI[0.76, 2.24]), and M1-R-M1-L ( P = 0.001, Hedges’ g=−1.77, 95% CI[−2.26, −0.98]).

Only the stroke group showed a highly significant difference when both time points were compared (Z = −2.936; p = 0.003), indicating the functional deficit after stroke.

While on a per-study level, this analysis failed to reach statistical significance, but for the proportion of ATTRv patients in ATTRACT, among the three trials, a highly significant tendency towards a higher proportion of male ( p = 0.003) and ATTRv ( p = 0.016) participants and was observed.

According to a paired t-test, the difference between AAs and EAs is extremely significant in both R-TMR (p = 0.003) and R-PHG (p < 0.000001).

CpG2 in OVAT is the only site representing slightly significant higher methylation levels in obese than in lean subjects ( P = 0.003).