Excerpts

In general, the difference in CYP2W1 expression between normal tissue and primary tumours was highly significant (P ≤ 0.0002).

This analysis showed a highly significant difference ( p = 0.0002), highlighting that fistulectomy improves the quality of postoperative evacuations by promoting more formed and regular stools than fistulotomy.

Contribution to the Next Years’ Spring Peak We investigated the correlation between the abundance of the spring generation (dependent variable) and the abundance of either of the two generations the year before (independent variables) with a multiple linear regression model: the contribution of the second generation to the abundance in spring next year is highly significant ( R 2 = 0.80, P < 0.0002), while the contribution of the first generation is not significant ( R 2 = 0.17, P = 0.21) ( Figure A8 a).

The total signs in February 2020 was 6.2% (10/162) and the total signs in the control group over all months was 1.4% (12/837), which is highly significant ( p =0.0002).

Comparison of relative T m of soluble HLA monomers with normalized anti-HLA MFI values generated by the cell-based assay revealed a striking and highly significant correlation at peptide concentrations of 100 μM (R = 0.87, p = 0.0002) and 10 μM (R = 0.85, p = 0.0004) ( Figures 3 D and 3E).

While our finding of an increased incidence of DQA1*03:01 in the cases (OR 2.81 [1.36–5.81], p = 0.005) is very similar to the findings reported for this class II allele in the previous study, we obtained no evidence for a significant alteration in HLA‐B*57:01 frequency among our cases and instead see a highly significant increase in frequency of the HLA‐B*44 family (5.33 [2.45–11.61], 2.5 × 10 −5 ), including a strong association with the B*44:03 allele (6.01 [2.37–15.28], p = 0.0002).

Using a meta-regression model (Section 2, Model 1) where publication date is the sole moderator, we find that the date of publication demonstrates a negative trend that accounts for 91.8% of the heterogeneity between studies (B = −0.166 [−0.254, −0.078], Q m = 13.72, p = 0.0002, k ES = 14 effect sizes, n = 206, τ resid = 0.110, see Figure 2A and Table 3 ).

Interaction terms X1X2 ( p = 0.0285) and X2X3 ( p = 0.0202) were moderately significant, with X2 2 showing a non-linear impact ( p = 0.0002).

Results Participants characteristics The PIR exhibited a highly significant correlation with the risk of DR ( P = 0.0002).

acidophilus , for the duration of their hospital stay and saw a highly significant decrease in both NEC and NEC-related death ( p <0.0002 and p <0.005, respectively) ( Table 1 ).

With covariate adjustment quiescent ulcerative colitis patients demonstrated a highly significant 55% lower number of colonic tuft cells as compared to controls (95% CI, 31–71%, P = 0.0002).

The only positive results were observed in a subgroup with a high rate of spontaneous mutation in CTCs, with a clearly significant RR (83 vs. 33%; p = 0.0002) [ 56 , 70 ]; Olaparib–Abiraterone.

However, lower pressure still resulted in highly significant release of the REMIS markers from the brain ( Fig. 2e , left-most panel, P = 0.0002, n = 7, ratio-paired t test).

This trend was highly significant ( P = 0.0002), partly because of a large sample size (550 pictures), yet not very steep ( b = −0.057).

Epidermal growth factor (EGF) levels were reduced upon treatment with BA significantly compared to the untreated GU group, whereas the CT/BA NPs-treated group showed a higher decrease by 56% below GU group, a highly significant difference; P = 0.0002.

Water Relations For the reductions seen for midday leaf water potential (ψ) in ungrafted and grafted plants, salinity (i.e., salt stress) and date of measurements proved to be highly significant factors ( p = 0.0002, p < 0.0001, respectively).

To reduce the bias of time to HSCT2 we analyzed only patients having HSCT2 within 6 months of relapse and found that having HSCT2 was a highly significant predictive factor in this univariate analysis ( P =0.0002).

A highly significant association was observed between IDH 1 status with respect to OG (p = 0.0002) and astrocytoma (p = 0.005).

Interestingly, our data revealed that a highly significant increase in myocilin expression (11.8-fold) was observed in TM region of the responder eyes compared to vehicle-treated eyes ( p = 0.0002); and there was a fourfold increase in myocilin expression in GC responder eyes ( p = 0.0004) compared with GC non-responder eyes.

1 B, there was a highly significant correlation (R = 0.74, p = 0.0002) between body weight and liver PAR2 expression in PAR2 ΔHep mice vs. wild-type (WT; PAR2 fl/fl ).

A clearly significant difference between the two groups could be noted (F(1, 204) = 14.2; p = 0.0002).

Applying repeated measures of variance methodology, a highly significant difference could be seen (F(1, 204) = 14.3; p = 0.0002) ( Figure 2 ), where those on active treatment exhibited higher e-GFR as a result of the treatment.

cereus HKS 1–1 was highly significant ( p < .0002) among the test strains. 3.2.2 Antibiotic sensitivity test The strains of B. cereus were found susceptible to different antibiotics (Table 2 ) in the Epsilometer test (E‐test) method, which was referred as an authentic way of high‐throughput sensitivity detection by Turnbull et al.

The difference between the 2 groups was highly significant ( P < .0002).

Notably, the lowest tested concentration of HYAL (0.015 U/ml) demonstrated a highly significant induction of HAS2 expression compared to medium control (Fig. 2 b, p = 0.0002).