“did not reach statistical significance”

Although the results of metformin (MD: −0.18; 95% CrI: −0.39 to 0.032) and bioactive metabolic regulators (MD: −0.15; 95% CrI: −0.37 to 0.077) did not reach statistical significance, both showed a decreasing trend in HbA1c, ranking second (SUCRA = 0.75) and third (SUCRA = 0.70), respectively.

In our sample, older pilots also had higher resting SBP and DBP, and there was a slight trend toward greater SpO 2 reduction in those with higher baseline BP, although this did not reach statistical significance.

Supernatants from microglia exposed to EVs loaded with let-7e or miR-548b-3p showed an increasing trend of TNF release, however, those TNF release levels did not reach statistical significance.

Hypertension showed a trend toward association but did not reach statistical significance.

Weekly intercourse frequency showed a trend toward being lower in the SPE group but did not reach statistical significance ( P = 0.062).

For changes in total palatal volume (ΔTV), sagittal displacement of the maxillary central incisors relative to the vertical reference line (ΔU1⊥VRL) showed a positive trend toward volumetric increase, although this association did not reach statistical significance ( p = 0.068).

GluN2B expression also showed a trend toward a decrease; however, this change did not reach statistical significance (Fig. 7a, c ).

The proportion of helper T cells (CD3 + CD4 + ) showed a decreasing trend but did not reach statistical significance (Fig. 5 C and G).

Functional status Within-group analysis in the TECAR group showed a trend toward improved lower extremity functional scores over time, although this change did not reach statistical significance (p=0.058).

In addition, the difference in change from baseline between the groups (Extended Data Table 1a ) showed a trend toward a reduction in arterial inflammation in the low-dose IL-2 group compared to placebo, but did not reach statistical significance (−0.103, 95% CI −0.22 to 0.02, P = 0.086).

Interestingly, while prior antibiotic use showed a nonsignificant trend toward poorer outcomes (HR = 1.44; 95% CI = 0.90–2.31), it did not reach statistical significance in this model.

Compared to the Control group, mice in the Antibiotics-only group showed a trend toward increased levels of albumin and MMP9 in the hippocampus, although these changes did not reach statistical significance (Supplementary Fig. 1H ).

In the primary model adjusted for age, duration of surgery, and urgency of procedure (elective vs emergency), the SAS showed a trend toward association with major postoperative complications, although this did not reach statistical significance.

Although the differences in VAS and Lysholm scores between the two groups did not reach statistical significance after four weeks of intervention, the effect size analysis and percentage changes indicate a clear trend toward functional improvement in favor of LL-BFRT.

The age distribution showed an increasing trend in vaccination rates with age (21.3% in individuals aged ≥60 years), although this did not reach statistical significance (p = 0.104).

In addition, p16 protein levels showed an increasing trend in old myoblasts, although this difference did not reach statistical significance ( Fig 1b ).

Significant differences were observed between the two subtypes in terms of sex ( p = 0.003), PSQI ( p = 0.0004), SAS ( p < 0.0001), and SDS ( p < 0.0001), whereas age showed a trend toward difference but did not reach statistical significance ( p = 0.064) ( Table 2 ).

In this cohort, DLRT showed a trend towards better survival than CLSLRT in RLD patient undergoing lung retransplantation for BOS, although this did not reach statistical significance.

Co-localization of BNIP3, BNIP3L and phospho-BNIP3L with mitochondria basally showed a trend toward being reduced, however, due to large variability between both controls and patients this did not reach statistical significance ( Figure 5 and Supplementary Figure 6 ).

The length of hospital stay showed a slight increase in the risk of infection-related mortality, with an odds ratio of 1.014 (95% CI: 0.998–1.030); however, this association did not reach statistical significance (p=0.078), indicating only a trend towards significance.

For the primary endpoint of all-cause mortality or HF readmission, the NSAIDs-related group showed a trend toward improved outcomes, although the difference did not reach statistical significance (hazard ratio [HR] 0.569, 95% confidence interval [CI] 0.289–1.118; p = 0.102).

Notably, the low-dose rhCol III group (5 μg/mL) showed a trend toward reduced ROS fluorescence but did not reach statistical significance ( p = 0.0554), which may reflect a smaller effect size at low exposure, limited statistical power, and the known methodological limitations and sensitivity of commonly used fluorescent probes ( 68 , 69 ).

A slight trend of higher plasma corticosterone concentrations in 3xTg-AD mice was observed, although it did not reach statistical significance ( p > 0.05). 3.3.

In contrast, levels of lysosomal proteases cathepsin L+V (CtsL+V) were significantly reduced, while lysosomal acid lipase (LAL) showed an increasing trend that did not reach statistical significance ( Figure 1 A).

Patients with higher P3H2 transcript expression showed a trend toward longer survival compared to those with lower levels; however, this trend did not reach statistical significance ( Figure 1 b).