“did not reach statistical significance”

Although differences did not reach statistical significance (probably due to the small number of patients), there was a clear trend for increased cholesterol, LDL, waist circumference, and body mass index values in the patients with suboptimal adherence in our study.

Although these associations did not reach statistical significance, the odds ratios demonstrated an increasing trend.

For 1‐year MACCE, GBM yielded an AUC of 0.7475 compared with 0.667 for TCAB, suggesting a favorable trend though the difference did not reach statistical significance.

However, drug use showed a lower P = 0.109, hinting at a possible trend, though it did not reach statistical significance.

Notably, Angle α and Angle β , which directly characterize the acuteness of the Cupid's bow apex, showed a decreasing trend post‐treatment (from 126.5° ± 14.0° to 120.8° ± 5.5°, and from 120.5° ± 10.9° to 116.6° ± 7.7°, respectively), though these changes did not reach statistical significance ( p > 0.05). 3.4 Different Age Group Lip Cases These three cases illustrate how identical treatments yield distinct outcomes based on age‐specific anatomical needs (Figures 5 , 6 , 7 ).

The standard-intensity group showed a trend toward increased risk, but this did not reach statistical significance (HR = 3.876, 95% CI: 0.846–17.758, P = 0.081).

Although MFN1 showed a trend toward increased expression with GDF15 treatment, these changes did not reach statistical significance.

Of note, the blastocyst formation rate exhibited a decreasing trend with higher TyG quartiles; in Q4 compared with Q1, the adjusted difference was − 2.37% points (β = − 2.37; 95% CI, − 4.78 to 0.03), which did not reach statistical significance, and other quartile contrasts were likewise non-significant.

Camre-chemo also showed a strong trend toward prolonged PFS (HR = 0.31, 95% CrI: 0.06–1.66), although this did not reach statistical significance due to wide credible intervals.

Compared to the ICL group, the PSS group showed a trend toward reduced microbial diversity; however, this difference did not reach statistical significance (Shannon index: p = 0.065; Simpson index: p = 0.066).

Kaplan–Meier analysis for overall survival showed a trend toward poorer survival in the high-risk group but did not reach statistical significance (log-rank p = 0.2; Fig. 10 C).

Serum RNASE1 levels were significantly higher in patients with severe disease activity compared with those with inactive disease, whereas patients with mild or moderate activity showed a trend toward increased RNASE1 levels that did not reach statistical significance ( Figure 2C ).

Short-term fasting (≤3 days; k = 15) showed a trend toward reduced triglyceride levels (g = −0.335; 95% CI: −0.684 to 0.013), although this effect did not reach statistical significance.

Correlation of PIK3CA mutations with outcome Patients enrolled in the G3 trial who had tumours with PIK3CA mutations showed a trend towards worse invasive disease-free survival (iDFS) compared to those with PIK3CA wild-type tumours, although this difference did not reach statistical significance (HR 2.1 (95%CI 0.95–4.78); p = 0.066) (Fig. 4 ).

Although OWDTO groups demonstrated a slight trend toward greater PTS increases, these differences did not reach statistical significance (Table 3 ).

Although the results showed a trend towards a reduction in sedentary time and an increase in MVPA when the PAL lesson was implemented, these variations did not reach statistical significance.

A notable trend favoring the Tr + RHT arm was seen in patients ( n = 39) who received five or more cycles, although this did not reach statistical significance (HR 0.60, 95% CI 0.30-1.18) ( Supplementary Figure S1 , available at https://doi.org/10.1016/j.esmoop.2026.106921 ).

The incidence of rescue analgesia use showed a decreasing trend from Group C (33.33%) to Group L (21.92%) and Group CL (16.00%), although the difference did not reach statistical significance ( P =0.053).

In multivariate analysis, tumor grade emerged as the only independent predictor of OS (HR 1.82, 95% CI 1.10–3.01; p = 0.018), while endocrine sensitivity showed a trend towards significance but did not reach statistical significance (HR 1.62, 95% CI 0.99–2.63; p = 0.052).

While the low dose (0.27 g kg −1 ) effectively decreased the TNF‐α level (66.13 ± 15.93 pg mL −1 , p = 0.0005, Cohen's d = 1.88), its effect on IL‐6 reduction (4.51 ± 0.27, p = 0.058, Cohen's d = 0.91) showed a strong trend but did not reach statistical significance.

Specifically, the CYP2C9*2 allele was significantly linked to increased hypoglycaemia risk (OR ≈ 1.85), while the CYP2C9*3 allele showed a trend toward increased risk, but this did not reach statistical significance in the pooled analysis [ 90 ].

Although our data showed a trend toward higher MEP amplitudes in the M1 proper region, this difference did not reach statistical significance.

SBP and HR changes The crystalloid group showed a trend toward higher incidence of hypotension both pre- and post-delivery, though these differences did not reach statistical significance compared to the combination group.

A positive trend towards more pronounced improvements from baseline to the end of the observation period were observed in the overall INKA group and female subgroup compared to the control groups, although these differences did not reach statistical significance [−12.5 (SD 20.17; n = 22) in the INKA group vs. −7.89 (SD 20.15; n = 62) in the control group ( p = 0.359) and −13.56 (SD 19.22; n = 18) in the female INKA group vs. −8.72 (SD 22.29; n = 43) in the female control group ( p = 0.4254)].

Pooled analysis showed a trend toward increased risk in the corticosteroid group compared with control, although this did not reach statistical significance (RR 1.30; 95% CI: 0.80–2.11; I 2 = 0%).