“did not reach statistical significance”

Regarding age, using the 50–59 age group as the reference, the 30–39 age group had a significantly higher GHQ-12 score (IRR = 2.18, 95% CI: 1.05–4.56, P = 0.037); the < 30 age group also showed a trend toward higher scores, though it did not reach statistical significance (IRR = 2.15, 95% CI: 0.95–4.85, P = 0.067).

Although IGFBP7 did not reach statistical significance (p > 0.05), its high expression still showed a trend towards poorer prognosis (Fig. 2 A, B).

In early-stage NSCLC population, although a negative trend was observed, it did not reach statistical significance at any percentile.

Analysis according to overall clinical stage showed a trend toward higher EpAb3-5-assessed EpCAM expression in advanced-stage disease (Stage III-IV) compared with early-stage disease (Stage I-II), but this difference did not reach statistical significance (Figure 2 C).

CRP did not reach statistical significance (95% CI, 0.496-0.732; AUC=0.614; P=0.071), although it showed a trend toward predictive relevance.

Starvation led to progressive body weight loss in both groups, and Trim24 −/− mice showed a trend toward more rapid weight reduction over time, although this difference did not reach statistical significance under the conditions tested ( Figure S4B ).

These findings indicate a positive trend favoring the treatment group on expository language outcomes; however, this difference did not reach statistical significance after adjusting for baseline oral narrative language ability. 9.6.

CLDN6 expression showed a trend toward shorter PFS but did not reach statistical significance ( p = 0.096).

In contrast, patients with PE exhibited significantly higher methylation levels in T compared with D tissues ( p = 0.035), while A tissues showed a trend toward higher methylation compared with D tissues, although this difference did not reach statistical significance ( p = 0.052).

Although CNS-specific ORR, CR, and PR did not reach statistical significance, the data showed a strong trend favoring KGIs and a significant reduction in CNS progression as the best response.

Patients in the UP group had a lower rate (13.3%) of both complete pathological response (pCR) and recurrence or death events (18.8%) compared with the DOWN group (22.8% and 25.9.%, respectively), although this shows a clear trend the difference did not reach statistical significance ( Fig. 1E , F ).

Further subgroup analyses revealed that, regarding assessment tools, studies using the MoCA demonstrated a significant therapeutic effect (MD = 1.622, 95%CI: 0.566–2.679; I 2 = 15.5%), whereas the MMSE subgroup (comprising four studies) showed a trend favoring the intervention but did not reach statistical significance (MD = 1.541, 95%CI: −1.486–4.568; I 2 = 90.1%).

Although AT2 cells showed a decreasing trend in In-F, the difference did not reach statistical significance, and AT1 cells did not show a consistent reduction in spatial abundance.

Urban residence showed a trend toward higher acceptance, although the association did not reach statistical significance after adjustment.

This was not observed for bipolar pulses, where B cell percentages showed an increasing trend but did not reach statistical significance.

Although the moderate activity group showed a positive trend (β = 0.010; 95% CI − 0.004 to 0.023), it did not reach statistical significance.

The relative abundances of Bacteroides, Rikenellaceae_RC9_gut_group , and Christensenellaceae_R-7_group tended to increase in the TEO 300 group compared with the control group, whereas Mediterraneibacter and Faecalibacterium showed a decreasing trend; however, these differences did not reach statistical significance ( P > 0.05).

While RMC-6272 treatment showed a trend toward reduced heart weight-to-body weight ratios, the reduction did not reach statistical significance ( Fig. 5 E).

The pertuzumab-alone group showed a trend toward an increased apoptotic cell population but did not reach statistical significance.

CWI at 1 h [MD = −31.26, 95%(-63.60,1.07), P = 0.058] and 24 h[MD = −44.75,95%(-92.98,3.48), P = 0.069] had a decreasing trend in reducing CK effect, but did not reach statistical significance.

Changes in visual acuity and macular edema were secondary outcomes in our study, showing only a mild trend toward improvement that did not reach statistical significance.

In multivariable analysis, abnormal chest radiographic findings showed a trend toward association with respiratory support, although this did not reach statistical significance.

Although the overall difference did not reach statistical significance, VDAC1 expression showed an increasing trend in the gain and amplification groups relative to deletion and diploid groups (Figure 4 E).

While re-osseointegration height and defect BIC did not reach statistical significance among groups, both parameters showed a decreasing trend from CEBM/BMP2 to CEBM and then to OFD.

Although the change in periapical cone cut location did not reach statistical significance ( p = 0.058), an overall trend toward improvement was observed.