Barely Significant
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did not reach statistical significance

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In the literature

While the OA/HA group also showed a trend toward cartilage preservation (Week 12: 6.5 ± 2.08), this did not reach statistical significance compared to the OA group at any time point. 3.3 Immunohistochemical Analysis of Cartilage Metabolism and Inflammatory Markers 3.3.1 Type II Collagen (COL II) Expression COL II expression followed a treatment‐dependent pattern throughout the study period (Figure 2 ).
An overall trend toward an increase in BMI was observed at the long-term follow-up that however did not reach statistical significance due the small sample size, but in the majority of participants BMI changes were stable or improving over time [ 80 , 81 ].
In order to test whether this was a reflection of a general increase in histone density, we further examined the density of histone H2B but did not find a reproducible increase in the RTT patient samples on any loci, and a slight trend toward higher histone H2B occupancy did not reach statistical significance ( Fig. 3B ).
Griffith et al, 40 who performed a meta-analysis of the effect of calcium on blood pressure, found a small statistically significant effect of calcium on lowering systolic blood pressure independent of baseline blood pressure, and a small trend toward reduction in diastolic blood pressure that did not reach statistical significance.