The OR of 1.32 for PNPLA3 -rs738409 and HCC risk in the combined Ghanaian and Nigerian populations did not reach statistical significance but suggests a positive trend.
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“did not reach statistical significance”
In the literature
A decreasing trend in serum SOD levels was noted with increasing severity of premature canities; however, it did not reach statistical significance [Tables 3 , 4 and Figures 1 , 2 ].
The concentrations of serum periostin, IL-5, and Der p sIgE and the RQLQ nasal and eye symptom scores showed a decreasing trend but did not reach statistical significance with SCIT treatment.
Another study has shown a decreasing trend of respiration in neural progenitor cells (NPCs) derived from BD patients’ iPSCs, although the results did not reach statistical significance [ 18 ].
The univariate Cox proportional hazard estimate for overall survival by ESR2 expression was 0.54 (95% CI 0.06, 5.22), suggesting a positive trend that did not reach statistical significance in this numerically limited cohort ( Figure 6C ).
The PaO 2 showed a trend toward faster recovery at t = 5 min after d-amphetamine administration but it did not reach statistical significance (saline: 57.7 ± 12.0 mmHg, d-amphetamine: 75.4 ± 14.6 mmHg, p = 0.0501, n = 9).
ACT scores showed a favorable trend in both groups, with a medium between-group effect size favoring the intervention (d = 0.42), although this did not reach statistical significance.
The use of radiotherapy showed a trend towards reduced LR risk but did not reach statistical significance (HR 0.37, p=0.066).
A previous history of transient ischaemic attacks or stroke also showed a trend towards increasing prevalence across BMI categories; however, the numbers were small and the differences did not reach statistical significance.
When comparing the expression of functional molecules between two groups, TNF‐α and IL_10 exhibited elevated expression in the IA group (although some did not reach statistical significance, they displayed an increasing trend) (Figure S3 ).
GLP-2 caused a significant increase in TRL-TG accumulation over the 6-h fat feeding period, whereas GLP-1 caused a decreasing trend; however, this did not reach statistical significance.
Although FF-MAS, T-MAS, and 24-OH-CHO showed a trend toward elevation, these differences did not reach statistical significance, potentially due to the limited sample size (Supplementary Material 4 , Fig.
5a ) showed a trend toward decreased food intake although this did not reach statistical significance (P = 0.061, acute experiment).
Similarly, while CFU-E colony numbers showed a trend of increase with SRT2104 treatment (no SRT2104, 27.1%±4.7%; SRT2104, 35.7%±8.3%), this difference also did not reach statistical significance ( Fig. 4A ).
While the OA/HA group also showed a trend toward cartilage preservation (Week 12: 6.5 ± 2.08), this did not reach statistical significance compared to the OA group at any time point. 3.3 Immunohistochemical Analysis of Cartilage Metabolism and Inflammatory Markers 3.3.1 Type II Collagen (COL II) Expression COL II expression followed a treatment‐dependent pattern throughout the study period (Figure 2 ).
An overall trend toward an increase in BMI was observed at the long-term follow-up that however did not reach statistical significance due the small sample size, but in the majority of participants BMI changes were stable or improving over time [ 80 , 81 ].
Correlation analysis showed a trend toward consistently reduced BMD with increasing age across all 3 regions but did not reach statistical significance.
In order to test whether this was a reflection of a general increase in histone density, we further examined the density of histone H2B but did not find a reproducible increase in the RTT patient samples on any loci, and a slight trend toward higher histone H2B occupancy did not reach statistical significance ( Fig. 3B ).
Griffith et al, 40 who performed a meta-analysis of the effect of calcium on blood pressure, found a small statistically significant effect of calcium on lowering systolic blood pressure independent of baseline blood pressure, and a small trend toward reduction in diastolic blood pressure that did not reach statistical significance.
HAR showed a trend toward increased DANE risk, although it did not reach statistical significance (OR, 1.59, 95% CI, 0.86-2.96, P = .140).
a negative trendgold
Umbilical artery pH demonstrated a negative trend with increasing sFlt-1/PlGF values; however, this association did not reach statistical significance after adjustment (estimated change −0.0076 per doubling; p = 0.070).
a positive trendgold
Association Between Serum Lycopene and Total Sperm Motility For total sperm motility, lycopene supplementation showed a positive trend that approached but did not reach statistical significance (SMD = 0.28, 95% CI [−0.04 to 0.61], p = 0.083).
There was a slight trend toward a greater percentage of games started posttreatment, but this did not reach statistical significance.
Although this study showed a positive trend for successful eradication in patients using a kit, it did not reach statistical significance.
Paroxetine and promethazine showed a trend toward ameliorating arsenite-induced FUS-eGFP SG phenotypes in SL P525L neurons ( Figure 7 E), although the effect did not reach statistical significance.