In line with the above-mentioned hypothesis, the amplitudes of the sEPSCs increased significantly in two lines (MCtrl = 22.5 ± 6.5; MPsi 96 hrs; day 10=30.7 ± 4.8, Figure 5D ; MCtrl = 15.9 ± 4.5; MPsi 96 hrs; day 10=27.6 ± 10, Figure 5—figure supplement 1B ), and the frequencies showed a trend to increase similar to Figure 5B , reflecting enhanced network activity (MCtrl = 1.0 ± 1.0; MPsi 96 hrs; day 10=1.5 ± 1.0, Figure 5D ; MCtrl = 1.5 ± 1.7; MPsi 96 hrs; day 10=1.0 ± 0.7, Figure 5—figure supplement 1B ).
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Although laser-assisted TLE showed a trend toward higher pooled proportions of SVC laceration than rotational TLE in both the pre- and post-2016 periods, these differences were not statistically significant ( Supplemental Figures 4 and 5 ).
Notably, patients who received niacin showed a trend towards increased NAD in leukocytes post-treatment while the same was not evident in tumors, suggesting the possibility of prominent NAPRT1 levels in the normal leukocytes compared with the tumors (Supplemental Fig.
Though not statistically significant in these data, TET1 showed a trend toward downregulation in the tissue resident myeloid cells, while CCL8 was found to be significantly increased in the bulk-RNA seq analysis, and trending towards upregulation in the myeloid compartment.
Histologically, ILA-treated mice showed a trend toward reduced epidermal thickness and fewer Munro microabscesses ( Figure 3K and L ).
For yield components, the number of siliques per plant and number of seeds per silique of rapeseed under each phosphate fertilizer treatment showed a trend of S2 > S1, with that under S2 being 0.29–37.98% and 5.73–22.6% higher than S1, respectively.
Nutritional risks in elderly patients undergoing lung cancer surgery showed a trend of first increasing and then decreasing, reaching a maximum at the day before discharge and remaining at a high level between the day before discharge and the 1st month postoperatively.
Although sarcopenia prevalence did not differ significantly, PD patients scored higher on the SARC-F overall and across most domains, performed worse on SPPB balance, and showed a trend toward lower handgrip strength and appendicular skeletal muscle mass index across quantiles, with a significant reduction in muscle mass at the 40 th percentile.
Before the administration of the second or third doses, antigen-specific Bmem frequencies showed a trend towards increase, with a robust rise following the subsequent doses (Fig. 4B , C).
The activity tracking by the Garmin watches showed a trend of more cardio and strength activities for the female group although the male group tended to expend more average calories per activity.
For the remaining endpoints, including V60, V75, V100, and the additional % V-matrix, the spacer group consistently showed a trend toward reduced rectal dose exposure compared with the no-spacer group ( Fig. 2 ). 3.
While raw NLR showed a trend toward positive correlation, a statistically significant association was observed with log-transformed NLR ( Figures S1 and S2 ), supporting its relevance as a marker of molecular disease activity.
The LBR showed a trend toward increase but without significant difference.
Previous studies within paediatric dermatology showed a trend towards higher satisfaction following video consultations than telephone; however, most were service evaluations and these modalities have not been compared in a trial. 17–21 It should be noted that most of our survey participants had experienced telephone consultations (92%), associated with higher levels of dissatisfaction, compared with video consultations (28%), which may have contributed to the preference for face-to-face appointments within our sample.
No significant differences were observed between groups with normal and elevated glucose levels or between sexes, although age (p = 0.0598) and glucose (p = 0.0569) showed a trend.
Interestingly, total IgE was higher in coinfected children and malaria-specific IgE responses in the coinfected children showed a trend of negative association with P. falciparum parasite density, with IgE to α-gal and MSP3 having a statistically significant negative correlation with parasitemia, even though the levels of antigen-specific IgE responses were not significantly increased in this study group.
Consistently, LPC 18:2 markedly increased Il17a and Il17f mRNA expression and showed a trend toward higher Rorc levels, although the latter did not reach statistical significance ( Fig. 5 E ) .
A subgroup analysis of three distinct follicular sizes showed a trend toward increased oocyte maturation rates in small follicles (< 13 mm) in the dual-trigger group, although this was not statistically significant.
For the other anesthetic types, GA showed a trend towards a lower likelihood of PLP when compared to the GA+PNB group.
In the present study, the UGT1A4 rs11888492 intronic variant showed a trend toward improved DFS in the multivariate analysis.
Mmp2 showed a trend toward upregulation, whereas Col1a1 expression was not significantly changed ( Supplemental Figure 1D ).
In LEAP-017, patients without liver metastases showed a trend toward improved OS (HR, 0.65; 95% CI, 0.42–0.99), whereas those with liver metastases derived minimal benefit (HR, 0.91; 95% CI, 0.72–1.15; ref. 25 ).
The OARSI score also began to increase two weeks after UAC and showed a trend of continuous increase, indicating that the cartilage matrix continued to be lost during the progression of TMJOA ( Figure 3 ).
In PC1-PC2 space, DNMT3A mutant samples showed a trend toward warmer tones (higher LPMD values of 0.40-0.42), whereas wild-type samples predominantly displayed cooler tones (lower LPMD values of 0.35-0.37).
These analyses showed a trend toward upregulation of differentiation markers such as CHGA , SYP , PNMT , and TH in the Dex condition, with SYP reaching statistical significance.