If group differences on any alcohol or clinical/personality measures showed a trend or significant effect, we used this measure in separate regression analyses against the imaging data.
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In the literature
The MHC-I protein level showed a trend to downregulation, and the mRNA level was significantly decreased.
A subgroup analysis according to age (75–85 years [n=148] and >85 years [n=38]) showed a trend toward greater improvements in pain control and bowel function in the subgroup aged >85 years ( Figure 4 ).
Using the suggested 3 genes from BestKeeper showed a trend to higher levels of TFB1M in BA 8 from subjects with schizophrenia (Fig. 5d ), NormFinder did not reveal any significant variation with diagnoses in that cortical region (Fig. 5g ) whilst using reference genes suggested by geNorm showed a strong trend to lower levels of NOL9 in subjects with schizophrenia (Fig. 5j ).
Of the protein C SNPs analyzed, the AA genotype of the rs1799810 SNP showed a trend toward increased mortality (26 % vs. 19 %) compared with the TT/AT genotypes, but this trend was not statistically significant ( p = 0.18).
Intraperitoneal insulin tolerance test performed at 12 weeks of age showed a trend toward increased insulin sensitivity in male ( Fig. 3 G ), but not female ( Fig. 3 H ), ΔF508 homo- and heterozygous mutant mice.
Treated mice also showed a trend of reduction of ParaThyroid Hormone (PTH) ( Figure 3f ), decrease of osteoclast number over bone perimeter and osteoclast surface over bone surface ( Figure 3g – i ), and reduction of mRNA expression of osteoclast-specific genes ( Figure 3j ), which are in agreement with the reduced serum levels of TRAcP ( Figure 2d ).
There were no significant differences between WT and PD-1KO mice although the latter group showed a trend for fewer antibody-secreting LLPC ( Fig. 1c ).
Electrocardiogram showed a trend toward increased QT intervals at 90 mg/kg/day groups.
In the current study, wild-type fibroblasts showed a trend towards decrease in the maximal OCR within 30 min of 1 mM PQ treatment which was preserved in the Surf1 −/− fibroblast. t -BuOOH and H 2 O 2 did not result in any changes in basal OCR, maximal respiration, or reserve capacity.
To inflammatory parameters, we observed a reduction of 8.3% in the levels of CRP (from 3.0±2.2 to 2.2±1.3; p=0.07) and of 17.4% in IL-8 (from 84.8±55.5 to 48.8±18.8; p=0.058), both showed a trend toward statistical significance.
Levels of MFN1 showed a trend toward an increase in vehicle-treated gp120 tg mice compared to non-tg mice (Fig. 6a , d ), and treatment with FK506 significantly increased levels of MFN1 in gp120 tg mice (Fig. 6a , d ). mtHSP70 was detected as a single band at approximately 72 kDa (Fig. 6a ).
The strong tACS condition showed a trend for the same effect (eyes open > eyes closed; F(1, 16) = 4.21, p FDR < 0.100).
The NHE patients showed a trend of impaired neurocognitive function, compared with HCs, whereas MHE patients produced significantly worse performances in all PHES subtests, resulting in lower PHES score, as compared to the other two groups.
In contrast, the IL-1β (+3954C/T) polymorphism showed a trend towards increased risk in Caucasians but no association in Asians.
A one-sided test was used because the semiquantitative analyses showed a trend towards a greater antigen burden in furious rabies [ 2 ].
The Kaplan–Meier survival curve showed a trend for high expression of Bcl-2, Bcl-xL and Bcl-w to be associated with shorter overall survival time ( Supplementary Figure 1B ).
The prophylactic treatment of 3-month-old 3 × Tg-AD mice showed a trend toward the generation and maintenance of relatively stable and adequate antibody levels over a 7-month period after the last vaccination.
6-methyl-5-heptan-2-one and geranylacetate showed a trend toward increased responses in starved flies but did not reach statistical significance (data not shown).
The prognosis of liver failure is still poor, but the spontaneous survival rate showed a trend of steady rise in recent years.
On day 3, Cx-43 showed a trend of increased accumulation in CNH-Col groups (0.05 and 0.1 mg/ml) compared with that in the collagen group, but only in the 0.1 mg/ml group was the NC accumulation visibly increased.
The other topographies, 80 and 333 nm, also showed a trend towards increased OPN and OC expression compared to controls, but this did not reach statistical significance.
The top SNP associated with DSM-5 cocaine use disorder (rs9298626) in the whole SAGE dataset was significantly associated with DSM5 cocaine use disorder in the COGA subset and showed a trend in the same direction in the FSCD and COGEND subsets.
Based on linear regression models without the interaction term between age and genotype, the volume normalized ocular rigidity showed a trend of increasing with age, but it did not achieve statistical significance (p = 0.17).
Persson et al 36 also showed a trend toward reduced (∼7%) neuritic length in dorsal root ganglia neurons expressing the M932L/V991L mutant channel, although this finding did not reach the level of statistical significance.