Excerpts

This trend was maintained albeit with borderline significance for aoSMCs (20% vs. 10%, p = 0.07, Fisher’s exact test) ( Figure 3 b).

There were no significant differences in the subject characteristics (as outlined in Methods), though age was nearly significant ( p = 0.07).

FACS analysis showed that in LPS-injected mice treated with 1-PPA, only the activated CD8/totalCD8 ratio was significantly lower than in LPS-injected mice ( p = 0.048) ( Figure 6 D3), while the activated CD4/totalCD4 ratio showed a trend to be lower in untreated LPS-injected mice ( p = 0.07) ( Figure 6 D2).

EAE-mice treated with “in/out” enriched-aCSF exchange therapy at days 6–8 following EAE-induction showed a trend towards a lower average clinical EAE-score at days 9–11 post EAE-induction (repeated ANOVA (f(1,16) = 3.73, p = 0.07), with a t -test for day 10 (4 days after starting treatment/2 days following end of treatment) revealing a significant difference in the average clinical score between treated and untreated mice (0 vs. 1.08 ± 0.30, respectively, p = 0.012).

Age showed a weak trend toward influencing Tc levels ( p = 0.07), with older patients slightly more likely to have higher concentrations. eGFR, an essential marker of kidney function, was not significantly associated with Tc levels in this model ( p = 0.11), suggesting that other factors, such as genetic variations, may play a more direct role in influencing drug concentration.

Under RT conditions, the AIP mice showed a trend of reduced glucose uptake rate compared to the WT mice ( p = 0.07; Figure 4 B,C), reaching statistical significance in those receiving the B. coagulans -supplemented diet, probably because they dissipated less energy under fasting and room-temperature conditions.

4/12 in stage I + II; p = 0.007) and showed a strong trend toward higher ISUP grade (3 + 4:21/28 vs. 5/12 in 1 + 2; p = 0.070).

Although the impact of 10 μg/mL KP1019 on lag was blocked at pH 6, multiple linear regression analysis revealed that the overall impact of pH on lag only approached significance ( p = 0.07).

Although circulating blood monocyte count above the median in our study was associated with peripheral atherosclerosis of only borderline significance (OR 1.8; 95% CI 0.9–3.3, p = 0.07), the combination of this parameter with higher Lp(a) levels ( ≥ 30 mg/dL) was observed almost three times more frequently in patients with peripheral atherosclerosis than in patients without atherosclerosis (27% vs. 10%, p < 0.01), indicating synergism between inflammatory and lipid factors.

Apoptosis in the model presented an association with fibrosis of borderline significance ( p = 0.071; β-coefficient = 0.420), independent from the other variables (data not shown in the table).

In the FXTAS individuals with an APOε2 allele, a marginal significance was observed towards a larger decline in verbal IQ (VIQ) in individuals with an APOε4 allele compared to those without an APOε4 allele ( p = 0.071).

HIF-1alpha at T1 showed a trend toward better OS, with a median of 101 months in T2 + T3, whereas it was not reached in T1 ( p = 0.071).

GEP44 We ran a two-way ANOVA in order to examine sex differences with respect to drug treatment, which resulted in a near-significant overall effect of sex [F(1,78) = 3.350, p = 0.071] and a significant interactive effect of GEP44 and sex to elicit weight loss [F(1,78) = 10.779, p < 0.01].

Tukey’s multiple comparisons test showed that plasma KC/GRO levels were significantly greater in the 1 cGy group compared to the 10 cGy group ( p = 0.05); this difference approached significance for the comparison with the sham-irradiated rats ( p = 0.071).

Real-time qPCR analysis overall confirmed the RNASeq data in NW subjects, with a borderline significant positive correlation (R 2 = 0.7726, p -value = 0.0717) only in the NW-AA group.

T2DM: Only EPI showed a near-significant ( p = 0.072) sex difference, with higher levels in females.

In contrast, IL-2 ( Figure 5 a) and IL-4 ( Figure 6 a) rapidly returned to baseline by D2, whereas IFN-γ ( Figure 5 c) exhibited an increasing trend at 48 h post-SA treatment ( p = 0.072).

No significant differences in the expression of hsa_circRNA_100837 were observed, even if their p reached a value near to significance when it was adjusted for sex and age ( p = 0.072) When stratifying all subjects by gender, we noted significant differences in the levels of circRNAs between AD and HCs both in males and in females in circRNA_102049 and circRNA_050263.

Correlation Between OGG1 Protein and 8-Oxo-2′dG Levels The level of 8-oxo-2′dG in the Ce of old controls showed a trend of positive correlation with the OGG1 protein level (R = 0.844, p = 0.072, Supplementary Table S9 ).

In gemcitabine-treated early-onset disease, TP53 mutations were present in 86.7% of tumors, compared with 40.0% in non-treated early-onset tumors ( Table S5 ), representing a strong trend that did not meet statistical significance in this small subgroup ( p = 0.0726).

Distance travelled, rearing and digging were lower in HFD-P compared to HFD-C, trending towards significance for digging at 12 weeks (−54.1%, p = 0.0728).

For one trait, Pearson’s linear correlation approaches statistical significance, and an inverse negative correlation is observed between total methylation island levels and the NEO-FFI Extraversion scale (r = 0.118; p = 0.073, Table 3 , Figure 1 and Figure 2 ). 3.

The 5-year survival analysis showed a trend of a higher survival rate in patients with high M3R expression (46%) than patients with low M3R expression CRC (42%) ( p = 0.073).

In parallel to the reduced density of activated/reactive microglia at 98 dpi, TMEV-infected Mmp12 −/− showed a trend ( p = 0.073) for a reduced density of M1 (CD16/32- and CD107b-positive) microglia, while no difference regarding the density of M2 (arginase I- and CD107b-positive) cells was observed.

There was a substantial effect of time after infusion (F (2,18) = 50.8, p < 0.0001), but time after lesion or sham-operation was not a significant factor (F (1,9) = 1.0, p = 0.34), nor were there differences between extracellular DA levels contralateral to lesion v sham-operation group, although there was a notable trend toward an increase in striatum contralateral to lesion (F (1,9) = 4.1, p = 0.073).