Excerpts

However, we found a negative trend between number of older siblings and ALL diagnosed at age 0–4 years (OR per sibling 0.85, 95% CI 0.68–1.06; p = 0.141) and a positive trend for ALL diagnosed at age 5–9 (OR 1.34, 95% CI 1.05–1.72; p = 0.019), with some evidence for an effect modification (p-value for interaction = 0.040).

Note that rs2071861 was only nominally significant ( P = 0.019, Table 3 ) in the discovery phase.

In particular, the difference between Group 1 and Group 3 was highly significant [median: 37.28 (IQR: 33.53–38.37) vs 16.06 (IQR: 9.979–29.27); p = 0.0193].

In the case of PRELID1 , there was a significant trend (R = 0.3932; p = 0.0196) towards higher copy number assignments for samples with DNA input amounts above the average (13.28 ng; range 2–120 ng) of the sample set ( Figure 3 ), even after removing outliers (>75 ng input DNA).

The efficacy of combination therapy was highly significant when compared to ABT-737 (p = 0.0198) and 9.2.27-PE38KDEL monotherapies (p = 0.0100; Fig 5A ).

A Kolmogorov-Smirnov test shows that the H 2 O 2 and the DTT evoked increase in Po of the mutant channel is moderately significant (P = 0.02 for H 2 O 2 and 0.03 for DTT).

None of these symptoms were significant predictors of long COVID in the adjusted model ( Table 3 ) (sleep disturbance was the only symptom category that approached significance ( p = 0.02)), however ME/CFS, joint pain, and several others demonstrated high variance inflation factors (S1 Table D.4 in S1 File ) indicating possible underestimation of their effects (S1 Appendix D in S1 File ).

At the middle site there was a highly significant decrease in PON2 expression in the labour group when compared to the non-labour group for both the 62 kDa form (p = 0.02) and the 43 kDa form (p = 0.006).

Planned comparisons revealed highly significant differences between the actual and predicted values (for 2 objects: t(25) = 2.6, p = .02, g = 0.46; for 3 objects: t(25) = 2.1, p = .05, g = 0.55; for 4 objects: t(25) = 6.9, p<.0001, g = 1.05; for 5 objects: t(25) = 7.4, p<.0001, g = 1.45).

N2 time window (260–380 ms) The three-way interaction between group, language, and task failed to reach significance ( F (1, 40) = .74, MSE = 7.34, η 2 P = .02, p> .05), indicating that inhibition may not come into play during the language task schema competition phase.

The 2 group×3 stem type ANOVAs on response time to speech stimuli yielded marginally significant main effects of stem-type (F1(2,68) = 4.64, p<.02, F2(2, 29) = 2.20, p<.13).

Significant or marginally significant associations were observed at the marker rs11629841 with children's orthographic judgments at ages 7 and 8 years (all P values<0.020).

The overall pooled effect size of the static balance function in the experimental group did not significantly differ from that in the control group [Hedges’ g: 1.32 (95% CI: -0.41, 3.06) at p = 0.13], with a highly significant difference in heterogeneity ( I 2 = 81% at p = 0.02).

In the FFM ME-TRAP group IFN-γ levels showed a trend to elevation at 1 week and 3 months after the last dose of vaccine with the increased responses significant at 1 week ( P = 0.02) when compared with baseline levels.

Outcomes that were promoted in the review were more likely to be significant than if there was no discrepancy (relative risk 1.66 95% CI (1.10, 2.49), p = 0.02).

The Cox-proportional hazard ratios with exact partial likelihood to handle tied failures for hospital mortality comparing the BMI categories <18.5, 18.5 to 22.9, 25.0 to 29.9, and ≥30.0 with the reference category were 1.13 (0.88 to 1.44), 1.03 (0.84 to 1.26), 0.96 (0.76 to 1.22), and 0.68 (0.43 to 1.08), respectively, with a highly significant test for trend ( p = 0.02).

Pimecrolimus treatment increased the externalization of both CD203c and CD193 on the surface of cells isolated from hymenopteran venom allergics (but not healthy controls) following stimulation with high doses of venom (1.0 μg*ml -1 ), leading to a 4.3–6.6% increase in the frequency of SSC low CD203c + CD193 + , SSC low CD203c + and SSC low CD193 + cells (borderline significance—paired t -test p = 0.02, = 0.08 and = 0.02, respectively).

In contrast, for headings 30°, 60°, and 90°, the improvement was either significant or approaching significance (p = 0.02, p = 0.12, p = 0.04, respectively; paired t-test).

A marginally significant difference between males and females ( F 1,36 = 6.37, p = 0.02) was identified, with males having on average, higher post-participation Overall Health scores when adjusting for pre-participation score, age, diagnosis and military service era.

Serum Ang-1 levels did not change significantly in cholecalciferol group (mean change: 1.36 ng/ml; 95% CI: -2.39 to 5.11 ; p = 0.280; Table 3 ) while in placebo group showed an increasing trend (mean change: 5.63 ng/ml; 95%CI: 0.51 to 10.75; p = 0.020).

Another study [ 37 ] used a complex intervention consisting of health professional and patient education (written information, family history collection proforma), documentation (EMR documentation of referral for GC/GT and testing protocol pathway) and systems (scheduling GC appointments directly at gynaecology clinic) showed a trend towards the intervention for GC referral (+27.4 (95% CI 11.1–43.7) p = 0.02) and completion of GT (+20.6 (95% CI 5.9–35.4) and towards the control for completion of GC (-27.8 (95% CI -46.7 to -9.1)) and identifying hereditary cancer (- 17.9 (95% CI– 40.9–5.1) p = 0.17).

It included regions belonging to the lateral occipital cortex, the occipital pole (all p < .05, FDR corrected) and a part of the left fusiform gyrus that nearly reached significance after correction for multiple testing (p = .02, uncorrected).

This association remained marginally significant with multivariate logistic regression; OR 1.0 (95%CI; 1.0–1.1, P = 0.02) ( Table 3 ).

This indicates a decreasing trend of vancomycin resistance among E . faecium from broiler flocks in the first years of surveillance (χ 2 = 5.8 p = 0.02).

When dividing IgM anti-PC levels into quartiles, there was a significant trend across the quartiles for the presence of multi-vessel disease with decreased levels of IgM anti-PC (p = 0.02), identifying a threshold for IgM anti-PC at the 25 percentiles, 24.6 U/ml, thus IgM anti-PC were divided into high and low levels at the 25 percentiles.