Excerpts

Also, since the results were only marginally significant, they are probably false-positive findings.

3 and 4 , there does not appear to be a clear trend that viremia or use of ARV results in loss of antigen presentation ability compared to uninfected controls.

This was lower than the LAP of wild type rescuants (19.9 s, 16.7–24.0), but the differences were not quite significant at the 5% level ( wt vs.

Multivariate analysis revealed that only optimal surgery was an independent prognostic factor for PFS in the discovery dataset ( Table S2 ) and that there was marginally significant correlation between debulking status of primary surgery and PFS time in the external dataset ( Table S2 ).

Because none of the interactions with correctness or matching approached significance (all F s<1), the effects of these factors seem to be unrelated to memory performance.

By comparing these residue levels across the matrices, an interesting trend emerges with regard to in-hive versus externally-derived pesticides.

However, only the HA+NP group elicited a response against NP protein, and that was marginally significant at best.

However, there was a highly significant positive correlation between the frequency of peripheral blood Vα24 + CD1d TM + and Vα24 + 6B11 + NKT lymphocytes ( Figure 1D ), confirming a dominance of invariant NKT lymphocytes in the CD1d TM + T lymphocyte population.

However, cotransfection with the pooled TRIM3 shRNA constructs led to a highly significant increase in GFP-Shank1A fluorescence ( Figure 1A, B ).

Unexpectedly, the trans group also exhibited a decreasing trend according to increasing inter- loxP distance ( Fig. 6A ).

The effect of per capita academic productivity remained highly significant when controlling for expenditure and for characteristics of study: broad methodological category, papers testing one vs. multiple hypotheses, and pure vs. applied discipline ( Table 1 , Nagelkerke R 2 = 0.051).

FAM-MDR* assesses marginal significance of the best model by computing the empirical marginal p-value of the pair found.

With correction for main effects, PGMDR reports a different near-significant two-locus model involving rs2275703 in CASQ1 and rs1028583 in HNF4A .

GO analyses and GSEA revealed highly significant enriched functional gene categories for most of the clusters ( Tables S4 , S5 and S6 ). a) Non-transformed cells Genes whose response to 3D Matrigel culture (cluster 1+2; Figure 4a ; Table S4 ) was restricted to non-transformed cells were mainly related to ECM turnover, lipid and eicosanoid/prostaglandin metabolism, or cell differentiation.

The reverse effect remained, and was highly significant for knee (OR = 2.02, 95% CI = 1.27, 3.22) and other joint replacement (OR = 3.47, 95% CI = 1.52, 7.88), although just non-significant for hip (OR = 1.57, 95% CI = 0.97, 2.53).

All correlations between geographic and morphological distances were highly significant.

correlations are not significant, although approaching significance).

FstC also showed a slightly significant trend to low variation within species.

In addition, using this linear model we found that the lengths of 5′UTR and CDS do not significantly influence mRNA decay rates, and the size of 3′UTR is only marginally significant, suggesting specific elements rather than sequence length determine mRNA half life in C2C12 cells.

A model based upon dietary manipulations of the lactating mother Using pooled data from Control, LON and LUN groups of Cohort II, we show a highly significant correlation between fat mass at 10 days of age and 112 days of age ( Figure 6A R = 0.63), suggesting that 40% of the variance in adiposity at 10 days of age is associated with adiposity at 112 days of age after being fed a high fat diet for 8 weeks.

Despite the obvious requirement for transcriptional mechanisms to modulate the changes in mRNA levels for these genes of the cytoskeleton, no unifying pattern in the expression profiles of the major genes encoding transcription factors of adipogenesis was observed (Supplemental Figure S1 ) and the correlation coefficients of PPARγ with fat mass at 10 and 112 days of age were non-significant (R = −0.01 and 0.14, respectively) and showed only marginal significance with some of the genes of ATE ( Figure 6 ).

Even though the prednisone- and combination-treated groups showed a trend toward a decrease in serum CK levels, these changes were not statistically significant.

Surprisingly we did not see a decreasing trend in fibrosis of diaphragm in arginine butyrate-treated mice.

Analysis of liver sphingolipids showed a trend toward increased GL1 and GL2 in DIO mice compared to their lean counterparts, but overall there were no dramatic differences, and ceramide levels were unchanged.

Due to the multiple comparisons involved in this study, marginally significant associations should be interpreted cautiously.