Excerpts

[ 20 ] for qualitatively determining if the co-localization in diffraction limited fluorescence imaging may be significant.

Most of the genes in Table 1 are highly significant (median q = .045) with a large fold-change (median magnitude of the fold change = 2.15).

The phenotypic variance explained by considering all imputed and genotyped SNPs for first visit measurement of blood pressure (V1) was 0.20 in EA (se = 0.03, P = 3.2x10 -10 ) and 0.49 in AA (se = 0.13, P = 7.9x10 -4 ) for SBP, and 0.27 in EA (se = 0.03, P = 5.2 x10 -11 ) and 0.37 in AA (se = 0.12, P = 3.9 x10 -5 ) for DBP: these were all highly significant estimates (Tables 2 and 3 ).

As well as progressive atrophy, we noted that atrophy first became measurable in the thalamus during the period of study and hippocampal volume showed a trend towards a significant volume change, although this did not survive correction for multiple comparisons.

In our investigation, the average ratio of maternal age less than 20 years was 0.9%; this ratio showed an increasing trend and reached the highest point (1.7%) in 2011.

The incidence of chromosomal aberrations exhibited a decreasing trend, which was probably related to the introduction of advanced noninvasive prenatal diagnostic methodology with subsequent induced abortion [ 37 ].

12 as inferred regulator(s) and 20 QTL in three major downstream groups, supported by 60 highly significant pairwise interactions ( S7 Table ).

The association with chronic bronchitis was borderline significant.

These data may explain why women with ER-negative and PgR-positive disease in the EBCTCG meta-analysis showed a trend towards initial benefit from adjuvant tamoxifen, an observation which was lost with longer follow-up.

In contrast to former findings [ 45 ], we did not detect an increase in full caspase-9 transcript levels upon administration of RA, BMP-4 or RA/BMP-4 double treatment ( S10 Fig ), however, observed a highly significant increase in caspase-9 cleavage activity following RA and BMP-4 administration, which was further increased by RA/BMP-4 double treatment.

No factorial interaction approached significance.

A significant trend was apparent between increasing cotinine levels and increased unadjusted odds of inhaled and food allergic sensitization.

Other two combinations of MRQ primer pairs, MRQ2/MRQ5 and MRQ2/MRQ4, also exhibited highly significant correlations with BRQ1/BRQ2 (R = 0.89 and R = 0.87, respectively) in terms of validating the quality of the 13 tested cDNA samples.

Housing construction, specifically open eaves and cement walls, increased the odds of infection, although these relationships did not quite reach statistical significance.

When further examining how the spring carbon balance responds to temperature changes for wet and dry years respectively, we find that much higher temperature sensitivity of net spring CO 2 uptake (in absolute values) is observed during wet years (-1.05 ppm·°C -1 , p = 0.08) than dry years (-0.43 ppm·°C -1 , p = 0.09; Fig 2 ), although the correlations between the net spring CO 2 uptake and temperature are marginally significant for both.

In addition, a nominally significant increase in the expression of several miRNAs was found in the 22q11.2 neurons that were previously found to be differentially expressed in autopsy samples and peripheral blood in SZ and autism spectrum disorders (e.g., miR-34, miR-4449, miR-146b-3p, and miR-23a-5p).

Given a significance threshold of 5%, this suggests that the correlation between FTR and savings is only marginally significant.

The non-obese and obese groups did not differ in gender distribution, but ethnicity distribution was different at a marginally significant level. β-cell function (DI) and insulin sensitivity (Matsuda ISI) were lower, and insulin secretion was higher, in obese relative to non-obese participants.

This finding as well as the near-significant relationship between PBF and delayed monetary reward discounting in non-obese women makes it tempting to speculate that non-obese women with relatively high body fat percentage, as observed here with monetary reward, may tend to consume foods that are easily accessible (more certain and more immediate) such as fast food relative to healthier meals that require time to plan and prepare.

It indicated that the lag 1 and 6 autocorrelations were marginally significant under level 0.1; lag 3 autocorrelation, however, was not significant.

Modest, sex-specific differences between groups included the trend towards a higher mean 24h ACTH in female offspring, and in males a significantly higher basal ACTH secretion in offspring and a borderline non-significant lower recovery EC 50 in the endogenous ACTH-cortisol dose-response relationship.

Link density and reciprocity Fig 10B reveals an increasing trend in the link density in all parts of the network.

Over the 1990s, we observe a decreasing trend of both Q d , w (C c ) and Q d , w (C m ), whereas the modularity of C s is rising except for the period of the global financial crisis in 2009.

In contrast to depression predicting incident asthma, this meta-analysis examining the effect of asthma on incident depression showed a trend toward increased RRs but did not reach significant difference statistically with high heterogeneity.

However, there was a clear trend towards fewer interventions (less need for treatment, fewer hospital admissions) associated with sevoflurane post-conditioning in patients experiencing any event.