Barely Significant
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did not reach statistical significance

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In the literature

Similarly, in Leone's VECTIBIL trial, the addition of panitumumab showed a trend towards enhanced overall survival (OS) advantage in ICC patients (15.1 months vs 11.8 months, p = 0.13) [ 23 ], although this result did not reach statistical significance.
The group with stage IB1 tumors >2 cm had statistically deeper cervical stromal invasion (9.99±5.04 mm, p<0.001, Kruskal-Wallis test), higher incidences of LVSI (45.3%, p = 0.002, chi-square test), and greater lymph node metastasis (24.2%, p = 0.002, chi-square test) compared to the other 2 groups (stage IA2 and stage IB tumors ≤2 cm).The group with stage IB1 tumors >2 cm showed a trend toward a higher incidence of parametrial invasion (9.5%, p = 0.14, chi-square test) compared with the other two groups (stage IA2 tumor, 0%;stage IB1 tumor ≤2 cm, 4%), though it did not reach statistical significance.
did not reach statistical significanceP = 0.153.0× alphaplainly factual
showed a trendP = 0.153.0× alpha
Although patients with elevated miR-96 expression levels showed a trend toward reduced survival probability, the Kaplan–Meier analysis did not reach statistical significance ( P = 0.15), so the sample size ( n = 79) may have contributed to insufficient statistical power.
did not reach statistical significancep = 0.153.0× alphaplainly factual
showed a trendp = 0.153.0× alpha
With respect to severe fibrosis, although serrated histology showed a trend toward lower rates of severe fibrosis, this association did not reach statistical significance in the multivariate analysis (OR: 0.49, 95% CI: 0.16–1.20, p = 0.15), likely due to the limited number of CSL cases presenting severe fibrosis in our cohort.
did not reach statistical significancep = 0.1523.0× alphaplainly factual
showed a trendp = 0.1523.0× alpha
While PDCD4 expression showed a trend toward better survival in high-expressing patients, it did not reach statistical significance (HR = 0.97, 95% CI: 0.94–1.01, p = 0.152, C-index = 0.589; Supplementary Figure S3 ).
A high VAT-M Z -score (more visceral fat) showed a trend towards being associated with a lower risk of a grade ≥ 3b postoperative complication in univariable (RR 0.47, 95% CI 0.16–1.36, p = 0.164) and multivariable analyses (RR 0.44, 95% CI 0.14–1.40, p = 0.166), but did not reach statistical significance (Table 3 ).