“showed a trend”

Interestingly, the 'one-carbon pool by folate' pathway, which contains the MTHFR and MTHFD1L genes, was nominally significant for bipolar disorder, showed a trend for major depressive disorder and was not significant for schizophrenia, suggesting that this pathway has distinct effect on mood disorders, probably through a common intermediate phenotype, such as ruminative response style.

Experiments with M21 melanoma xenografts (Figure 9B ) showed a trend for tumor growth retardation by tTF 218 -TAA either in the native or in a randomly TMS(PEG) 12 -PEGylated form.

Basal mitochondrial respiration was significantly decreased and respiration due to ATP turnover showed a trend towards reduction in RCAN1 ox islets ( S3B and S3C Fig ) demonstrating a consistent respiratory defect with RCAN1 overexpression across multiple aspects of mitochondrial function.

Results Overall, the results showed a trend toward less anxiety in patients who viewed the YouTube videos; this was exhibited by a reduction in the median GAD score by 1 point.

If group differences on any alcohol or clinical/personality measures showed a trend or significant effect, we used this measure in separate regression analyses against the imaging data.

The MHC-I protein level showed a trend to downregulation, and the mRNA level was significantly decreased.

A subgroup analysis according to age (75–85 years [n=148] and >85 years [n=38]) showed a trend toward greater improvements in pain control and bowel function in the subgroup aged >85 years ( Figure 4 ).

Using the suggested 3 genes from BestKeeper showed a trend to higher levels of TFB1M in BA 8 from subjects with schizophrenia (Fig. 5d ), NormFinder did not reveal any significant variation with diagnoses in that cortical region (Fig. 5g ) whilst using reference genes suggested by geNorm showed a strong trend to lower levels of NOL9 in subjects with schizophrenia (Fig. 5j ).

Of the protein C SNPs analyzed, the AA genotype of the rs1799810 SNP showed a trend toward increased mortality (26 % vs. 19 %) compared with the TT/AT genotypes, but this trend was not statistically significant ( p = 0.18).

Intraperitoneal insulin tolerance test performed at 12 weeks of age showed a trend toward increased insulin sensitivity in male ( Fig. 3 G ), but not female ( Fig. 3 H ), ΔF508 homo- and heterozygous mutant mice.

Treated mice also showed a trend of reduction of ParaThyroid Hormone (PTH) ( Figure 3f ), decrease of osteoclast number over bone perimeter and osteoclast surface over bone surface ( Figure 3g – i ), and reduction of mRNA expression of osteoclast-specific genes ( Figure 3j ), which are in agreement with the reduced serum levels of TRAcP ( Figure 2d ).

There were no significant differences between WT and PD-1KO mice although the latter group showed a trend for fewer antibody-secreting LLPC ( Fig. 1c ).

Electrocardiogram showed a trend toward increased QT intervals at 90 mg/kg/day groups.

In the current study, wild-type fibroblasts showed a trend towards decrease in the maximal OCR within 30 min of 1 mM PQ treatment which was preserved in the Surf1 −/− fibroblast. t -BuOOH and H 2 O 2 did not result in any changes in basal OCR, maximal respiration, or reserve capacity.

To inflammatory parameters, we observed a reduction of 8.3% in the levels of CRP (from 3.0±2.2 to 2.2±1.3; p=0.07) and of 17.4% in IL-8 (from 84.8±55.5 to 48.8±18.8; p=0.058), both showed a trend toward statistical significance.

Levels of MFN1 showed a trend toward an increase in vehicle-treated gp120 tg mice compared to non-tg mice (Fig. 6a , d ), and treatment with FK506 significantly increased levels of MFN1 in gp120 tg mice (Fig. 6a , d ). mtHSP70 was detected as a single band at approximately 72 kDa (Fig. 6a ).

Cirrhotic livers showed a trend of increased incidence compared with minimal fibrosis or perisinusoidal/pericellular fibrosis, though not statistically significant ( P = 0.05235 or P = 0.20697, resp.). 3.4.

This study also showed a trend towards poor survival in patients who were treated with immunosuppressants, especially intravenous high-dose cyclophosphamide.

JAK3 inhibition showed a trend toward reducing all the evaluated Th1 cytokines, but it is noteworthy that there were significant reductions in the secretion of TNF-α, IFN-α, and IL-17.

During the entire period of 1982–2012, many high-latitude regions showed a trend towards earlier BGS and delayer EGS, resulting in a longer LGS, but trends in PGS show a more fragmented pattern than BGS, EGS and LGS.

There were no evidence of heterogeneity among the studies (p= 0.860, χ 2 = 2.57, I 2 =0.0%). Four trials showed a trend towards a reduction in EDSS score during the IVIG treatment when compared to the baseline.

There was a trend toward hyperconnectivity among alpha sources located in sensorimotor cortex, while an alpha source in the cerebellum showed a trend of hypoconnectivity to multiple regions in the parietal and temporal lobes.

Factors such as publishing in non-chiropractic journals showed a trend towards improved quality of reporting scores, although this was not statistically significant in the multivariate regression analysis.

Blue-yellow CSFs showed a trend similar to red-green CSF up to 4 cpd, but at higher spatial frequencies (6 and 8 cpd) there were signs of luminance intrusion to chromatic aberration ( Figure 3B ).

Additionally, while the control flies showed a trend of reduced parasite load over the course of 12 days of infection, the flies defective in phagocytosis had a parasite load that increased over three days post-infection and remained elevated until day 12 ( Fig 2D ).