However, dnmt1 showed a trend of lower expression in LPS-stimulated groups.
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Although both normal weight (OR = 0.25,95% CI:0.06 ~ 1.03, p = 0.05) and overweight (OR = 0.11, 95% CI:0.01 ~ 1.25, p = 0.08) groups showed a trend toward reduced risk compared to the underweight reference group, these associations did not reach statistical significance in multivariable model.
Several parameters pertinent to mitochondrial respiration, including basal respiration, maximal respiration, proton leak and ATP production, showed a trend towards higher values in untreated OA subjects compared to untreated MA ones (see Figure 4 , upper part of panel A, “CTRL” bars).
In our study, the three different therapy modalities showed a trend of differences in OS, but this trend was not sufficient (no statistical difference).
10 months), earlier anlotinib use still showed a trend toward improved survival.
• ACO patients showed a trend toward greater improvements in the Asthma Control Questionnaire-5, Asthma Quality of Life Questionnaire, and modified Medical Research Council Dyspnea Scale scores.
Nevertheless, exploratory analyses showed a trend toward a higher incidence of POAF in patients undergoing surgery involving the left upper lobe, consistent with prior reports ( Table S1 ).
Other early complications, such as hemothorax (3.6%) and fever (1.4%), also showed a trend toward higher rates in older patients.
During adolescent development, ELS males showed a trend towards lower mean firing rates in PL which would have to be confirmed in a larger data set.
Furthermore, the ULK1 inhibitor SBI-0206965 showed a trend toward increasing tau puncta formation, whereas the ULK1 inhibitor XST-14 at 5 μM exacerbated intracellular p-tau aggregation but had no effect on degradation of preformed tau foci (Extended Data Fig. 10a,b ).
Consistent with these data, anti-C3a antibody treatment of aged mice significantly lowered IL-1β and monocyte chemoattractant protein 1 (MCP-1), whereas IL-6 showed a trend of reduction and TNF remained unchanged (Fig. 6g−i and Extended Data Fig. 8c ).
Note that chondroprogenitor cells in the SF zone of adult articular cartilage at P65, which exhibited reduced Ldha fluorescence levels, also showed a trend toward the lowest median fluorescence levels of Cs and pPdh ( Figures 3(B) , 4(B) and ( C )).
By 12 weeks, the HA group showed a trend toward increased bone formation compared to the Empty control group, although this was not statistically significant.
Notably, in an OF test, we confirmed that the anxiolytic doses of NPS retained a stimulatory effect in msPs, while the number of open arms entries and the distance travelled in the EPM showed a trend toward decreasing.
Carriers of the A1 allele of the Taq1A polymorphism (linked to the DRD2/ANKK1 locus), associated with reduced D2/3 receptor density, show higher risk for AUD; in an Indian male cohort, the A1 allele showed a trend toward association and a haplotype including A1 conferred an approximately 2.5-fold higher risk ( 146 ).
Overall, all HF subtypes showed a trend of decreased α diversity, but the degree of decrease differed: the decrease in gut microbiota diversity was most significant in HFrEF patients, while it was relatively mild in HFpEF ( Luedde et al., 2017 ; Beale et al., 2021 ).
Smokers experienced a significant improvement in OS, while non-smokers did not benefit even showed a trend towards deterioration.
In particular, false negative PD patients showed a trend toward higher NMSS scores and significantly greater autonomic and urinary burden than true-positive patients.
FcγRIIA-binding antibodies showed a trend toward enrichment for ARCT-154 recipients at the day 29–91 interval, with a few Spikes showing statistical significance compared to BNT162B2 recipients, but not nearly to the same degree as FcγRIIIA (Supplementary Fig. 6 ).
nucleatum- detectable cases also showed a trend toward increased T: A→A: T substitutions over F. nucleatum -undetectable cases (21.4% vs. 8.2%), although this association did not reach statistical significance ( P = 0.06, Table 2 , Supplementary Fig. 2).
For stage II and III patients, most of whom underwent mastectomy, postoperative radiotherapy showed a trend toward improved survival, but did not achieve statistical significance.
Notably, adults aged 40 to 59 years showed a trend reversal post-2007, with increases following a prior nonsignificant decline.
The addition of biomarkers to clinical variables showed a trend towards improvement in model performance, although this trend only met statistical significance for all-cause mortality in incident AF.
Lonner and co-workers noted that polyaxial constructs were associated with better maintenance of thoracic kyphosis compared with monoaxial or hybrid constructs, which showed a trend toward kyphosis loss; this observation highlights that the effect of screw type may be parameter-specific (i.e., affecting rotation or sagittal contours more than coronal Cobb correction) [ 9 ].
Age showed a trend toward increased risk but did not reach statistical significance.