Patients with t(8;21)/inv(16) without KIT D816 mutation showed a trend toward better OS than those intermediate without any genetic variants (the 2017 ELN, 2022 ELN, and 2023 CN all classified “genetic variants not classified as favorable or adverse” into the intermediate-risk group, so we defined these as “intermediate without any genetic variants”).
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With the exception of OePPO1 , all examined genes showed a trend toward higher expression in cv Bambina, although differences were statistically significant only for the two LOX family members ( Figure 2B ).
Patients with a primary tumor mitotic rate ≥ 6/mm [ 2 ] showed a trend toward a higher risk of BM, but this was not significant (OR, 1.75 [0.89–3.45]; p = 0.104).
Late PPM implantation showed a trend toward worse outcomes.
When cells cultured under stiff (4 mg/mL) conditions were treated with PXS-5505 for 7 days, transcript expression of JUN and FOS was significantly decreased, whereas CCN1 and MYC showed a trend ( Fig. 7G ).
In the remaining subgroups, serplulimab showed a trend of OS benefit, but the differences compared with the chemotherapy group were not statistically significant (all P>0.05).
In our experiment, MLR did not differentiate between LR and HR animals in the control group (0.05 units), and although experimental group MLR values (LR/HR: 0.06 units/0.10 units) showed a trend, they did not reliably reflect the reference range of inflammation intensity or correspond to identified histologically graded pathomorphological features of RA.
More recently fruquintinib also showed a trend of efficacy in refractory metastatic colorectal cancer patients [ 6 ].
Dobutamine and levosimendan caused a non-significant increase in MAP, while milrinone showed a trend towards a reduction in MAP [−3.46 (−7.27 to +0.35)].
In contrast, for OS, perforation (HR: 2.38, 95% CI: 0.96–5.88, p = 0.06) and pT4 (HR: 2.11, 95% CI: 0.86–5.14, p = 0.1) did not reach statistical significance but showed a trend toward worse prognosis.
The number of surgeries showed a trend toward reduction with steroids (OR = 0.48; 95% CI: 0.17–1.34) across 7 studies (1 RCT, 6 NRS; n = 10,951), but this was not statistically significant, with low certainty.
AAA-VoCs showed a trend toward higher cytokine production than C-VoCs.
Among the proposed biases, anger was linked to a more negative situation interpretation bias, impulsiveness to a more negative memory bias, and anxiety showed a trend toward a positive association with attention bias, indicating that as anxiety levels increase, so does the tendency to direct attention to positive elements within ambivalent CSs.
Consistent with gene expression data in this projection population, male mice showed a trend toward elevated tyrosine hydroxylase expression ( Figure 1I ) and higher levels of DAT compared with females ( Figure 1J ).
Basal membrane properties of mDA neurons (Boost+ versus Boost) by patch-clamp recording on day 60 showed no major differences, though Boost+ mDA neurons showed a trend toward lower input resistance, higher cell capacitance, and an increased spontaneous action potential (sAP) frequency ( Figure 2, C–F ).
In addition, Sirt1 knockdown showed a trend toward a 17.58% increase in the p-p65/p65 ratio compared with the Bmal1 overexpression group, although the difference did not reach statistical significance ( Figure 5D ).
EVs enriched in RoosterNourish‐MSC‐XF showed a trend of minimal increase in the protein content when compared to RoosterNourish‐MSC‐XF UCM, showing similar tread as particle numbers (Figure 3A ) suggesting Nourish medium is the richest medium in terms of protein content and particles followed by Mesencult‐ACF (Figure 3C,D ).
Conclusion: While propofol was associated with more hypotension, dexmedetomidine showed a trend towards more frequent bradycardia.
For example, supplemental analysis showed a trend that the relationship between positive affect and OCB‐Os tended to be stronger among employees when the sample was older than 39 ( ρ > 39 = .42; ρ < 39 = .30; Δρ = .12, 90% CI [.02, .22]) whereas this difference was not present for OCB‐Is ( ρ > 39 = .30; ρ < 39 = .32; Δρ = −.01, 90% CI [−.09, .06]).
Biochemically, 5XFAD/Tg4-42 hom mice showed a trend towards increased levels of insoluble Aβ4-x peptides in the hippocampus.
Overall, the estimates showed a trend of larger population size of A. troschelii than A. saxatilis beginning at 100 KYA.
These results showed a trend similar to that observed for muscle wet weight, indicating that VWR‐induced muscle adaptation was not impaired by PG‐PS treatment. 3.6.
Only the L/O ratio showed a trend toward higher values in the V-shape group, but this did not reach statistical significance.
However, the enfortumab-vedotin exposure-efficacy analysis showed a trend toward a better response at higher enfortumab-vedotin exposure quartiles (55–65% ORR for the upper three exposure quartiles vs 32% ORR for lowest exposure quartile).
Notably, SSA response rates showed a trend toward being higher in patients with GH/PRL adenomas compared with GH-only tumors (68.2% vs. 42.9%).