Excerpts

Furthermore, all groups showed an increase in IL-6 after stimulation, which was highly significant in the MNG group (Fig. 3D , third graph).

Statistical analysis showed that the relative volume difference, compared to the fresh state, was already highly significant from the first day of staining with Lugol’s iodine, whereas, for Hf-WD POM staining, the relative volume difference reached statistical significance only after 11 days of staining (Supplementary Fig. 1 ).

Gene ontology analysis on the differentially expressed genes revealed highly significant dysregulation of genes and processes involved in Wnt signaling pathway, wound healing, and acute inflammatory responses (Fig. 5a , Supplementary Data 9 ).

In monkey R there was also a positive trend toward higher salience for airpuff vs neutral objects that did not reach significance.

Unlike the airpuff objects, saline and time-out objects had similar salience to neutral objects or even a small trend toward negative salience (less salience than neutral) for the time-out objects using free viewing (Fig. 4c ) and consistently for both monkeys (Supplementary Fig. 6 ).

Notably, nicotine had near-significant interactions with the association between VPBs and both J and S amplitudes (Table 1 ), suggesting nicotine may modify the relationship between VPBs and early repolarization.

Both blue and green food webs showed a trend of decreasing nestedness with increasing elevation (Fig. 5 ).

Regarding direct effects, elevation positively influenced modularity (standardised coefficient: 0.49) and negatively influenced niche overlap (−0.53) in green food webs, while the opposite (−0.38 and marginally significant 0.10, respectively) was observed in blue ones (Fig. 3c ; Supplementary Table 7 ).

1b , the splitting at top of the valance bands is quite significant with out-of-plane M and ∆ E = 65 meV compared to the in-plane M with ∆ E = 0.7 meV.

For high effectiveness, the eliminated effect is very close to zero while for low effectiveness, it is positive at about 6 percentage points and close to being significant at the 5%-level.

When screening different macrolactamization sites, the ratio of isomer yields did not follow a clear trend.

Most significant pairwise differences among vegetation types include comparisons to either barren or boreal peat bog and differences among prostrate-shrub tundra, erect-shrub tundra and wetlands are not or only marginally significant (Table 1 ; Supplementary Table 4 ).

Fourier-transformed EXAFS analyses showed a clear trend that the intensity of Pt-Cl/Pt-S bonds gradually decreased as the annealing temperature rising, accompanied by the increased intensity of Pt-Pt/Pt-Co bonds (Supplementary Fig. 13 ), demonstrating the decomposition of coordination structures and the formation of alloys.

We have previously shown that although only Ag85A-specific IgG on Day 28 were associated with a significantly reduced risk of TB disease, Ag85A-specific IgG on Day −7 also showed a trend towards an association with reduced risk of TB disease that did not reach statistical significance 6 .

The coding rs1047781 variant has been reported to display a marginally significant association with an indicator of liver damage (AST/ALT ratio), but the association with absolute levels of AST or ALT is novel 39 .

The emergence of a significant trend in any TC metric at the global scale is noteworthy because it is unclear whether natural climate variability can modulate TC behavior at this spatial scale.

The ECE generally shows a decreasing trend with increasing trajectory length, although very short trajectories of T = 10 also achieved a low ECE, likely due to a high number of trajectories predicted with very low confidences.

Eight downregulated and five upregulated proteins (pN+ vs pN0) had a highly significant differential abundance according to the status of locoregional metastasis ( q = 3.25E-03 to 4.91E-02 for nine proteins; two proteins were exclusively detected in 50% of pN0 samples: CD209 and TGFB1I1) (Fig. 4d ; Supplementary Data 2-8 ).

The correlation of PARP1 copy number with PARP1 expression approached significance, suggesting that with a larger sample set we might find an association, as has been previously observed 76 .

Antibodies against E, another immunogenic antigen in the vaccine, showed a slightly increasing trend from the 3rd to the 4th dose (Fig. 2f ).

Moreover, this effect remained highly significant when instrumental variables were expanded to encompass all genome-wide significant non-HLA loci for serum IgA levels (inverse variance-weighted OR = 2.49 per SD of IgA level, 95%CI: 1.56–3.99, P < 0.001).

A significant positive correlation of the HAI and the MN titers was found for the H1N1 and H3N2 strains contained in the vaccine formulation, as well as a clear trend for the B strain.

Yet, if particle-attached NCD N 2 fixation is light independent, these low putative cell-specific rates and abundances may be significant when depth-integrated, considering the large expanse of the dark ocean 37 , 60 – 62 .

1H ′) showed a clear trend, with the highest rates immediately dorsal to the VF and steadily decreasing along the DV axis.

When investigating the GM volume changes across sessions, we observed a symmetrical pattern of highly significant group differences (Fig. 1 , Supplementary Table 1 ), and post hoc analyses revealed that each of these clusters reflected reductions in regional GM in the women who were pregnant between the time points (Supplementary Table 2 ).