In addition, group 1 showed a trend reduction in one of the cognitive performance indicators digital symbol test and trail making test compared to group 3 (dg_sym p-value = 0.055 and tmt_A_rt, p-value = 0.078) (Fig. 7d ).
In addition, we identified an increasing trend in sera neutralizing activity against Omicron BA.1 over time (p = 0.055, Conover-Iman test) (Fig. 6f ).
2i ), a marginally significant increase in approach speed (EYFP: 3.59 ± 0.28; hM4D: 5.24 ± 0.67; P = 0.0555, unpaired t -test) (Fig. 2j ), an increase in the mean duration of individual investigation (EYFP: 3.04 ± 1.16; hM4D: 7.258 ± 1.446; P = 0.0404, unpaired t -test) (Fig. 2k ), and a less percentage of stretched postures towards stimulus mice (EYFP: 86.22 ± 5.90; hM4D: 49.86 ± 6.71; P = 0.0006, unpaired t -test) (Fig. 2l ).
Administration of anti-Ly6G antibody significantly suppressed CCRK-induced PMN-MDSC accumulation in liver ( p < 0.01), leading to a borderline significant reduction in HCC tumorigenicity ( p = 0.0555; Supplementary Fig. 5e, f ).
Drug concentration showed a trend towards an effect on peak viral load and on AUC viral load ( p = 0.056 and p = 0.074, respectively, Fig. 3e, f ), suggesting that high concentrations could be associated with a reduction of viral load, with a nonlinear relationship.
A 6 (SNR) × 2 (group) mixed ANOVA on arcsine-transformed 22 accuracy revealed that older adults were less accurate than young adults irrespective of SNR ( F 1,30 =19.48, P <0.001), and accuracy increased with increasing SNR in both groups ( F 5,150 =399.10, P <0.001), with a marginally significant group × SNR interaction ( F 5,150 =2.21, P =0.056, Fig. 1b ).
Previous study showed that mucin-degraders (family Prevotellaceae) were enriched in patients with depression and anxiety 47 , and a further subgroup analysis of present study also supported a near-significant increase of Akkermansia in unaffected controls with antidepressant ( n = 5, P value = 0.056) when comparing to those without (Supplementary Fig. 9b ).
In comparison, the combined explained variance by soil properties (soil pH, C/N, and moisture) had a marginally significant negative relationship with latitude for soil fungal communities (Adj R 2 = 0.16, p = 0.056) (Fig. 6a ).
In addition, fox-urine exposed animals showed a trend of more freezing than non-traumatized animals (left, p = 0.056, lemon and air groups combined).
A marginally significant effect of condition, F (1,15) = 4.31, p = 0.056, η 2 = 0.22, revealed higher hit rates when earn colors were presented first relative to when save colors were presented first, specifically at shorter onsets (8 ~ 38), F (1,15) = 4.81, p = 0.044, η 2 = 0.24, where onset information was limited (left panel, Fig. 4a ).
Although not reaching the level of conventional statistical significance, two neuropeptides that showed a strong trend toward differential expression were RYa ( F 2,9 =4.033, P =0.056) and myosuppressin (MYO; F 2,9 =3.611, P =0.071).
Expected parasitism based on a binary regional food web was a marginally non-significant predictor of observed parasitism ( z =1.9, P =0.056, with a partial regression coefficient of 1.9 (s.e.=0.99) for binary data ( Supplementary Table 8a ), compared with 2.3 (s.e.=0.84) for quantitative data ( Supplementary Table 3 ).
1 ), a significant increase in sputum CD14 - CD16 - cDCs, and a strong trend ( p = 0.056) for an increase in CD1c + cDC2s, the dominant subset of sputum CD14 - CD16 − cDCs, was associated with human patent infection (Fig. 2D ).
The mean of the individual changes (Δ = V7–V1) in each of these metabolites was also significantly different between the NR and placebo groups, with the exception of NADP + , which, however, showed a strong trend after multiple testing correction ( p = 0.057; Supplementary Data 6 ).
CT-179-treated tumors showed a trend to decreased p-OLIG2 (p = 0.057), consistent with disruption of OLIG2 dimerization, and significantly reduced p-RB, indicating an overall decrease in proliferation (Fig. 5A ).
2c ) but showed a trend for larger litters compared with native backcrosses (native x immigrant F1-F4 pairs; t = 1.9, p = 0.057, 95% CI [−0.18, 2.02]; Fig. 2c ) although not statistically significant.
The interaction effect of stimulation status × type appeared borderline significance in ODD, f = 3.10, p = 0.057, η 2 = 0.09.
Expression of WNT11 correlated significantly ( p = 0.014) and FZD8 showed a trend ( p = 0.057) with increased biochemical recurrence (Supplementary Fig. 8b ).
Using the genes that contributed most to the enrichment of this upregulated gene set ( n = 48 genes), we built the first principal component (PC1) of their VAT bulk expression and identified a negative trend (rho = −0.242, p value = 0.057) between PC1 of the VAT bulk expression and the adipocyte diameter in RYSA (Supplementary Note 1.7 , Supplementary Data 43 ).
The methylation level between the benign and advanced-stage cancer groups was significantly different ( p -value = 0.011), while the difference between the benign and early-stage cancer groups was borderline significant ( p -value = 0.057) (Fig. 2e ).
This difference reached statistical significance in LNs (cervical and mesenteric) and gut tissues (colon and ileum), while PBMCs showed a trend approaching significance ( p = 0.057).
MBP staining within CD11b+ cells showed a strong trend towards less internalized myelin in plKO males at P15 compared to littermate controls ( p = 0.0571) (Fig. 6e ).
sensitized MAP comparison was nearly significant ( p = 0.0574).
The angular distribution of diurnal acrophases for H3K9Ac peaks proximate to such sites differed from those for peaks distant from such sites ( W =4,572.6, P =0.0136, n =664 samples), and the difference in angular distribution of seasonal acrophases showed a trend toward significance ( W =3,643.2, P =0.0576, n =664 samples).
Although the effect was nearly significant, decoding accuracy did not significantly increase with gradient order ( ⍴ = −0.03, p = 0.058, Spearman’s correlation).