Excerpts

4c ), whereas a comparison with the one-handers group showed a trend towards increased connectivity in amputees ( F (1,26) =3.274, P =0.082).

( P <0.022 in all cases), while marginally non-significant higher expression in cavefish was observed at the earliest sampled time point (10 h.p.f., P =0.083).

Post-hoc comparisons using the Bonferroni method revealed that 8-Hz stimulation significantly decreased freezing in ChR2-expressing rats ( p = 0.049), whereas the increase displayed by mCherry rats just missed significance ( p = 0.084).

In the matched cohort, similar to the total cohort, the interaction term for age (per 10-year increment) × SNA showed a trend toward statistical significance but did not reach it (HR 0.81, 95% CI [0.63–1.04], p = 0.084).

Accordingly, all results are robust, except that different perceptions of how “smart” the authors of the AI-generated (versus human-generated) messages were seen to be became non-significant ( p = 0.504) and “unique” became marginally significant ( p = 0.084) and therefore these results are not visualized in Fig. 2 .

Age-stratified PERMANOVA within the same timepoint comparisons confirmed this pattern: in 1–2-year-olds, Ill and Not-Ill children showed a trend toward divergence at D15 ( F (1, 178) = 2.32, p = 0.084, R 2 = 0.013, 95% CI [0.008, 0.030]) and significant separation at D85 ( F (1, 194) = 2.64, p = 0.049, R 2 = 0.013, 95% CI [0.008, 0.031]), whereas no significant separation was observed in the 7–12-month or >2-year groups at any timepoint (Fig. 2 ; Supplementary Table 9 ).

3f ), with a nonsignificant trend for DOPAC ( p = 0.085, Fig. 3d ).

Using this difference score as our dependent measure and group as fixed factor, we found a marginally significant main effect of group, F (2, 138) = 2.51, P = 0.085, ηp2 = 0.035 (this is analogous to an interaction effect using repeated measures ANOVA with a group factor and an age factor: the statistics are identical).

5D ) and a negative trending towards significance cluster in the SameSt group (370–710 ms; p = 0.085) (Fig. 5C ).

4b ), but the discrimination between familiar and unknown places, considering the 24 place-responsive neurons, was only marginally significant (54%, p = 0.085; permutation test; Fig. 4c ).

Meningiomas with 1p loss designated at the 50% and 75% thresholds were associated with significantly shorter median time to recurrence compared to those designated with WHO grade 2 meningiomas (both p < 0.05) while other 1p loss thresholds approached significance (5%: p = 0.085, 25%; p = 0.079, 95%; p = 0.056).

The CD8 + :FOXP3 + T cell ratio in ICI-non-resistant AYA melanomas was similar to the adult groups, while the resistant AYA group showed a trend of lower CD8 + :FOXP3 + cell ratio compared to adult non-resistant melanomas ( P = 0.085) (Supplementary Fig. 2d ).

To further validate this association, we assessed rs75326924 in an independent GWAS of a Korean cohort [19], observing a similar effect direction (BETA = −0.54) with a P -value approaching significance ( P = 0.086).

Marginally significant decreases over the studied period were found in Western Asia (−2.5%, p = 0.086) and North America (−7.2%, p = 0.093).

Plasmid DNA transfection of the same constructs showed a trend towards a low level of toxicity ( p = 0.086), and treatment with Triton X-100 resulted in complete loss of viability.

Adjuvant chemotherapy was significantly associated with decreased DMFS in the high-radiomic signature group ( p = 0.01), did not have a significant association in the low-radiomic signature group, and had only a marginally significant association among all patients ( p = 0.087) (Fig. 4a ).

Pre-treatment heterogeneity was also statistically significantly associated with overall survival in the Cox PH analysis (HRR 1.50 (95% CI 1.01–2.23), p = 0.046), though the Kaplan Meier log-rank test was only borderline significant ( p = 0.088, Fig. 4a ).

The gated channel activity term showed association with lung cancer risk with borderline significance (Fisher’s exact test, P = 0.088) (Supplementary Table 4 ).

In the PFC-MSC cluster, genes identified by Sherlock also showed a trend of significant co-expression ( P = 8.8 × 10 −2 ) with GWAS-significant genes (Supplementary Fig. 5a ).

In line with the enforced adipose glucose disposal in the fasted state, mice supplemented with GE showed a trend towards increased GLUT1 protein levels in the iBAT ( p = 0.089) but not iWAT (Fig. 6f, g ).

We also observed an increasing trend of PT from Luminal A to Luminal B and then to Her2 and Basal ( p = 0.089, Mann–Kendall Trend Test - MKT), consistent with the prior knowledge that non-Luminal subtypes are more aggressive with worse clinical outcome than Luminal subtypes (Supplementary Fig. 10d ).

Further, the match > mismatch contrast seemed to characterize the decrease better than the linear contrast, which was only marginally significant (contrast M = 0.005, SD = 0.014, CI: [−0.001–0.012], t (18) = 1.76, P = 0.09, Cohen’s d = 0.40, see Fig. 3 ).

Similarly, patients with positive energy metabolism change showed a trend towards better treatment response (OR = 1.36, 95% CI, 0.96 to 1.94; P = 0.09).

After additionally controlling for health-related variables, the results for both CVD and cancer mortality were still persistent, although the association between mixed group and all-cause mortality became marginally insignificant (HR = 0.91, 95% CI: 0.82–1.02, P = 0.09).

For sarcomas, 3/6 Δ122/Δ122 IL-6+/+ mice showed metastases to the gut, liver, spleen, pancreas or lymph node; 1/3 of Δ122/Δ122 IL-6+/− mice had a single metastasis to the heart; and 0/4 Δ122/Δ122 IL-6−/− mice had metastases, although this did not quite reach statistical significance ( p = 0.09, χ 2 -test; Table 2 ) due to low numbers of tumours.