Excerpts

After false discovery rate ( FDR ) correction, pathway enrichment analyses for genes harboring nominally significant ( p < 0.05) probes identified 44 significant pathways ( q < 0.05), and 5 pathways were related to lipid metabolism.

Some genetic variants of genes encoding crystallin proteins and antioxidant enzymes have been reported to contribute to the underlying mechanisms of ARC, but the reported results were only marginally significant ( p = 0.05) or non-significant [ 3 , 5 , 6 ].

Despite the overall reduction in morphine use, subgroup analysis demonstrated that administration of vitamin C through the oral route only showed borderline significance in this aspect ( p = 0.05).

Individually, the LN group showed a near-significant reduction in office systolic BP (−4.39 ± 2.19, p = 0.05), whereas the HN group alone showed no reduction in office systolic BP (−1.30 ± 2.92 mmHg, p = 0.66).

There was a trend towards an increase in the proportion of patients classified as sarcopenic; however, this did not reach statistical significance (OR = 2.4, 95%CI = [1.0, 6.0]; p = 0.05).

In the RBVD study, and only MDA showed a borderline significant association with smoking status ( p = 0.05, Table S1 ) and a significant association with CYMA ( p < 0.01, Table S3 ), regardless of the dietary group.

Small doses of allulose did not have a significant effect on HbA 1c and fasting insulin ( p > 0.05), while the reduction in fasting glucose was of borderline significance ( p = 0.05).

As shown in Figure 3 A, the 20 M-HP group crossed the platform the most times, 6.39 ± 0.46, which was a significant increase of 47.15% compared with the 20 M-C group of 4.32 ± 0.56 ( p < 0.05); the 16 M-HP group crossed the platform the most times, 5.31 ± 0.78, which was a highly significant increase compared with the 16 M-C group of 2.06 ± 0.34 ( p < 0.05), 157.77% ( p < 0.01); and the 9 M-HP group traversed the platform 4.95 ± 0.89 times with a highly significant improvement of 150% ( p < 0.01) over that of 9 M-C of 1.98 ± 0.14.

Moreover, a strong trend was demonstrated for decreased LDL cholesterol (100 ± 8 mg/dL (2.59 ± 0.21) to 93 ± 7 (2.40 ± 0.18); p = 0.05) and a decline in TC:HDL ratio from 4.0 ± 0.3 during control to 3.7 ± 0.2 during the fiber intervention ( p = 0.02) period.

With respect to the association between hemodynamic activations that differentiate the clinical group from the TD group (see Table S3a, S3b ) and ADHD severity scores, our results showed a marginally significant positive correlation (Spearman’s rho = 0.501, p < 0.05) between HbO values in right frontoparietal ROI in the 2-back condition and Conners’ ADHD index.

For hip fractures, the association of allium vegetables was borderline significant ( p = 0.050), but did not reach significance for cruciferous vegetables ( p = 0.157).

Food Patterns The Jonckheere–Terpstra test ( Table 2 ) revealed a significant increasing trend across neuropathy severity for the Western/fast-food dietary pattern (Z = 2.24, p = 0.03) and refined grains and starches pattern (Z = 1.99, p = 0.04) and a borderline significant trend for the alcohol and animal fat pattern (Z = 1.92, p = 0.05).

[ 43 ] when evaluating instrumental parameters in goat's milk yogurt containing only probiotics or probiotics with cupuaçu ( Theobroma grandiflorum ) pulp over 28 days of storage, showed a trend of loss of the texture of the product throughout the storage, being significant for apparent viscosity and firmness ( p < 0.05), although significant for consistency ( p < 0.05) for the yoghurt with only probiotic.

At 6 months, in multivariable analysis, women with a baseline HbA1c ≥ 8% were more likely to reach the primary endpoint [aOR 4.4 (2.1–9.3)] p < 0.001, while those with a BMI ≥ 35 kg/m 2 almost reached statistical significance [adjusted odds ratio, aOR: 2.0 (0.98–4.1)] p = 0.05.

[ 11 ] altered the results from borderline significant ( p = 0.05) to statistically significant ( p < 0.05).

In the unadjusted models, DISST insulin sensitivity was reduced in the HPHFib group, relative to the StdD group, at both week 4 and week 10, but the difference between diets did not reach statistical significance (i.e., p < 0.05) ( Table 4 ).

The weight of the tibialis anterior showed a decreasing trend in the DEX group ( p = 0.05) and was significantly decreased in the 2LDEX group compared with the control group; however, there was no difference between the DEX-treated groups ( Figure 3 G).

The long-term NATHAN 1 trial reported a marginal, borderline significant effect on the primary composite endpoint (NIS-LL, p = 0.05) without significant improvements in nerve conduction studies; therefore, evidence for functional stabilization is very limited and inconclusive.

Also at the beginning of the study, the median sIgE value in response to rMal d 1 was 0.99 kU/L (range 0.04–94.60 kU/L) The patients showed a significant decrease of the median sIgE in response to Bet v 1 (10.60 to 5.19 kU/L; p = 0.01) and a nearly significant decrease of sIgE in response to rMal d 1 (0.99 to 0.61 kU/L; p = 0.05) after 2 years of BP-AIT ( Figure 2 ).

This protective effect was then observed at week 12, as well as weeks 16, 18 and 20, while at weeks 14 and 21, the results were borderline significant ( p = 0.0501 and p = 0.052, respectively).

The differences in FGF 21 between HSI-I and HSI-non-I showed borderline significance ( p = 0.0503) after being adjusted for age and gender ( Figure 4 C). 4.

Regarding biomarkers of liver function, levels of total bilirubin, direct bilirubin and indirect bilirubin were unaffected by walnut consumption, although an increasing trend in total bilirubin and indirect bilirubin was observed in participants regardless of their group with a near-significant main effect of time ( p = 0.0505 and p = 0.0729), suggesting that academic stress may lead to a mild increase in total bilirubin levels.

In women, the carbohydrate intake was higher in the obesity group than the nonobese group, and the association of the carbohydrate intake with the obesity risk was marginally significant ( p = 0.0508).

The mean fullness score for the PGX (granules) meal was also significantly higher at time points 15, 30, 45, and 60 min (5.9, 5.7, 4.9, 4.3 respectively) than for the WD meal (3.5, 2.8, 2.2, 1.4 respectively) (all p < 0.01) and showed a strong trend towards being higher at 90 min ( p = 0.051).

In non-users, there were non-significant decreases in cardiovascular events in all treatment groups compared to placebo, and the reduction bordered on significance in the adjusted model for the combined EPA + DHA + ALA group ( p = 0.051).