On the contrary, on TNFAIP3 and CxCR4 expression, relapse had a quite significant effect (% of total variation ≥3.30, p ≤0.050), but not pregnancy (% of total variation ≤1.57, both p ≥0.6).
Excerpts
There was predominantly a candidate gene approach using common alleles, which despite small sample sizes (median 93 [IQR 40–222]) with no trend to an increase over time, generated a high proportion (74.5%) of nominally significant (p<0.05) reported associations suggesting the possibility of significance-chasing bias.
Statistical significance was determined using an unpaired Student t test and results were considered significant or highly significant when p ≤0.05 or ≤0.01, respectively.
Having a serious pregnancy complication is associated with higher quality of ANC, but this is only marginally significant (b = 0.22, p = 0.05).
Quantification of inflammatory cell aggregates (a hallmark of NASH) revealed that lobular inflammation was reduced by intervention with propagermanium ( Fig 4C ), with borderline significant effect of early propagermanium treatment ( p = 0.05 for HFD+Pro_6wk and p = 0.18 for HFD+Pro_12wk, respectively).
In the same time interval, an increase in BLI signal from the rest of the mouse as measure for development of metastasis ( Fig 2E ) was observed for LM2-4 (day 7.5: 3.8x10 6 ± 6.8x10 6 p/s, n = 12; day 21: 1.2x10 8 ± 1.4x10 8 p/s, n = 10; P = 0.03, t -test), but did not reach statistical significance for LM2-4H2N (day 7.5: 3.1 x10 6 ± 4.3 x10 6 p/s, n = 11; day 21: 8.0x10 7 ± 1.1x10 8 p/s, n = 10; P = 0.05, t -test).
The differences were considered to be highly significant at P ≤ 0.05.
The sex distribution between control (type PD) and hybrid (type HD) crosses is nearly significant (chi-square 6.00, DF = 2, P = 0.050), yet the difference is minor, given that all crosses are dominated by males.
As shown in Table 2 , although in our GWAS none of the two SOX6 gene SNPs achieved nominally significant p values ( p <0.05) for univariate association with BMI, FM or hip BMD, both SNPs achieved p values of 10 −6 to 10 −7 for bivariate association with BMI-hip BMD or FM-hip BMD.
Rapamycin-feeding resulted in a marginally significant increase in total sleep time (Treatment effect, p = 0.05) when the sexes were combined, but not when each sex was treated separately (females: Treatment effect, p = 0.10, males: Treatment effect, p = 0.26).
Eleven out of the 16 SNPs in this genomic area are nominally significant (10 −6 <p<.05) providing additional support for the involvement of EFNA5 in AD.
For DHETs, a decreasing trend was noticed in Tie2-sEH Tr compared to WT mice, which was significant in 8,9-, and 14,15-DHETs ( P < 0.05; Fig 3D–3F ).
Comparisons among mechanically-stimulated flies using this model were highly significant (P<0.05), indicating differences among sexes and lines as well as among treatments.
Most variables fluctuated without showing a significant trend of increasing or decreasing over time (i.e., NH 4 + , NO 3 − , BOM, conductivity, pH, precipitation, DSLS, and SOI; all p >0.05).
However, dunce 1 rescue with A0023-Gal4 was only marginally significant ( P = 0.05) compared to c309-Gal4 and D0264-Gal4 rescue.
This difference was marginally significant (χ 2 = 3.77, df = 1, P = 0.05).
However, baseline right hemisphere BA25 metabolism showed a marginally significant correlation with change from baseline MADRS, whereby higher baseline metabolism predicted better response to O/F therapy ( r = 0.68, P = .05).
approached significancep>0.05
aldrichi the excess of infected females approached significance (X 2 = 3.20, 0.10>p>0.05).
With the exception of the non-significant difference between the DMN and the single system ( X 2 = 2.54 p = 0.1) and the DMN and the δ-Single between-network connectivity (X 2 = 1.53 p = 0.2) which was likely explained by the relatively large overlap between the DMN and the single system, the results showed that the difference between the fc-behavior correlation coefficients of the two sets of networks was significant (or marginally significant) (Single-SMN: X 2 = 3.6, p< 0.05; Single-VN: X 2 = 5.69, p< 0.05; β-Single –DMN: X 2 = 4.78 p< 0.05; β-Single –SMN: X 2 = 6.64 p< 0.01; β-Single –VN: X 2 = 9.56 p< 0.01; δ-Single – SMN:: X 2 = 3.38 p = 0.06; δ-Single – SMN:: X 2 = 5.52 p< 0.05).
In adenocarcinoma cases only (test for heterogeneity by histology: p heterog = 0.066), the minor allele of CYP1B1 rs10175368 was significantly protective for lung cancer (OR = 0.8, 95%CI = 0.69–0.93, p trend = 0.003) and a similar protective effect was nominally significant (i.e. p-value≤0.05) for the CYP1B1 rs9341266 polymorphism.
One-way Anova analysis showed that intramuscular treatments effected the number of regenerating fibers by a quasi-significant level after one week of regeneration (df:3,19; F = 3.137, p = 0.05).
A marginally significant protective effect was observed in the 60–69 age group (unadjusted OR=0.62, 95% CI: 0.39–1.00, p = 0.050).
The remaining pair-wise comparisons were either not or only marginally significant (P<0.05).
approached significancep>0.05
The reduction in macroscopic lung PA was statistically signficant (p<0.05) for both BCG/MVA and SO2 treatment and approached significance (0.1>p>0.05) for BCG alone.
showed a trendp<0.05
Additionally, a few more channels that showed a trend-level difference (uncorrected p<0.05 but not remaining significant after FDR correction) were located approximately in the bilateral frontopolar ([FP]), dorsolateral ([DL]) and ventrolateral ([VL]) regions (uncorrected p<0.01; [FP] ch 36 (d = 0.83; 95%IC 0.19, 1.43), ch47 (d = 0.93; 95%IC 0.26,1.56