Barely Significant

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nominally significantp<0.051.0× alphagold
There was predominantly a candidate gene approach using common alleles, which despite small sample sizes (median 93 [IQR 40–222]) with no trend to an increase over time, generated a high proportion (74.5%) of nominally significant (p<0.05) reported associations suggesting the possibility of significance-chasing bias.
borderline significantp = 0.051.0× alphagold
Quantification of inflammatory cell aggregates (a hallmark of NASH) revealed that lobular inflammation was reduced by intervention with propagermanium ( Fig 4C ), with borderline significant effect of early propagermanium treatment ( p = 0.05 for HFD+Pro_6wk and p = 0.18 for HFD+Pro_12wk, respectively).
In the same time interval, an increase in BLI signal from the rest of the mouse as measure for development of metastasis ( Fig 2E ) was observed for LM2-4 (day 7.5: 3.8x10 6 ± 6.8x10 6 p/s, n = 12; day 21: 1.2x10 8 ± 1.4x10 8 p/s, n = 10; P = 0.03, t -test), but did not reach statistical significance for LM2-4H2N (day 7.5: 3.1 x10 6 ± 4.3 x10 6 p/s, n = 11; day 21: 8.0x10 7 ± 1.1x10 8 p/s, n = 10; P = 0.05, t -test).
marginally significantp< 0.051.0× alphagold
With the exception of the non-significant difference between the DMN and the single system ( X 2 = 2.54 p = 0.1) and the DMN and the δ-Single between-network connectivity (X 2 = 1.53 p = 0.2) which was likely explained by the relatively large overlap between the DMN and the single system, the results showed that the difference between the fc-behavior correlation coefficients of the two sets of networks was significant (or marginally significant) (Single-SMN: X 2 = 3.6, p< 0.05; Single-VN: X 2 = 5.69, p< 0.05; β-Single –DMN: X 2 = 4.78 p< 0.05; β-Single –SMN: X 2 = 6.64 p< 0.01; β-Single –VN: X 2 = 9.56 p< 0.01; δ-Single – SMN:: X 2 = 3.38 p = 0.06; δ-Single – SMN:: X 2 = 5.52 p< 0.05).
nominally significantp-value≤0.051.0× alphagold
In adenocarcinoma cases only (test for heterogeneity by histology: p heterog = 0.066), the minor allele of CYP1B1 rs10175368 was significantly protective for lung cancer (OR = 0.8, 95%CI = 0.69–0.93, p trend = 0.003) and a similar protective effect was nominally significant (i.e. p-value≤0.05) for the CYP1B1 rs9341266 polymorphism.
showed a trendp<0.051.0× alpha
Additionally, a few more channels that showed a trend-level difference (uncorrected p<0.05 but not remaining significant after FDR correction) were located approximately in the bilateral frontopolar ([FP]), dorsolateral ([DL]) and ventrolateral ([VL]) regions (uncorrected p<0.01; [FP] ch 36 (d = 0.83; 95%IC 0.19, 1.43), ch47 (d = 0.93; 95%IC 0.26,1.56