“did not reach statistical significance”

Apart from this association, all other associations did not reach statistical significance ( p > 0.008), and there was no suggestive evidence found at a relaxed significance threshold ( p > 0.05).

Although the decline in total B cells (CD3 − CD19 + CD20 + ) and naïve B cells (CD3 − CD19 + CD20 + CD27 − CD38 lo ) did not reach statistical significance, mature/activated B cells (CD3 − CD19 + CD20 + CD27 + CD38 moderate ) declined significantly from 313 (267–392) cells/10 5 lymphocytes to 64 (28–166), P = 0.008, and memory B cells (CD3 − CD19 + CD20 + CD27 + CD38 − ) decreased from 608 (380–842) cells/10 5 lymphocytes to 101 (36–200), P = 0.004 (Figure 4 ).

We also observed a similar trend for SLF I in the left hemisphere, but the effect did not reach statistical significance when multiple comparisons across tracts were taken into account (t 11 = 3.15, CI = 0.038–0.211, P = 0.009).

Inhibition The hierarchical regression analysis showed that, under the more stringent alpha level of 0.01, the association between parent ratings of total motor skills and inhibition among Taiwanese children with ASD did not reach statistical significance after controlling for covariates ( β = 0.26, p = 0.01).

The rise in hsCRP after GH-withdrawal did not reach statistical significance, but reinstitution of GHRT resulted in a decrease (p<0.01) in the hsCRP levels ( Table 3 , Figure 3H ).

The survival rate in the ECLS team group was slightly lower than that in the control group, but this difference did not reach statistical significance (P > 0.01) (See Table 4 ). 3.5 Complications and prognosis of ECPR patients in the two groups In the group of 29 patients who received ECPR, the utilization rates of mechanical ventilation, IABP, and CRRT were 100 %, 55.1 %, and 37.9 %, respectively.

Immediately after the VR module, the participants showed some increase in scores addressing positive attitudes and a decrease in scores addressing negative attitudes (but did not reach statistical significance) except for item 8 (scores: 1.89 ± 0.93 versus 1.58 ± 0.91, p < .01).

56.9%, p < 0.001), whereas among those already needing psychiatric treatment before the index date, difference by medical GR status did not reach statistical significance (70.9% in GR+ vs. 77.8% in GR−, p = 0.01).

RESULTS Both groups showed improvements in negative and positive attitudes, although the reduction in scores for the negative attitude domain did not reach statistical significance in the IL + SP group (for the SP group, P = .01 and < .001, respectively; for the IL + SP group, P = .15 and .01, respectively).

Surprisingly, the effects of excessive iron intake on serum and liver GSH or GSSG did not reach statistical significance ( Figure 5 e,f,h), while high iron significantly decreased the GSH/GSSG ratio ( Figure 5 g) ( p < 0.01), which also indicated that lipid peroxidation occurred in the mouse liver.

During sibutramine therapy, expression of miR-378 in SAT tended to increase but did not reach statistical significance, while in plasma, a reliable increase in the miR-378 level was revealed ( p = 0.01) ( Figure 1 C,D).

Utility of enrolment biomarkers in predicting recurrent shock and respiratory distress At ICU admission with shock, patients with higher Syndecan-1 levels were more likely to develop recurrent shock (OR = 1.82, 95% CI 1.07–3.35, P = 0.038); however, after adjustment for multiple comparisons, the association did not reach statistical significance (at our predefined level of P < 0.01).

While the median age varied among the groups, the difference did not reach statistical significance (P>0.01).

The relationship was such that higher BIS was associated with lower synaptic strength ( Figure 5 ). Correlations between BAS variables and EPC did not reach statistical significance, but there were trend level negative associations between EPC and BAS drive (Rho = −0.45, n = 14, p = .011).

Although this difference did not reach statistical significance ( χ 2 P = 0.012), it supports several other studies that note a general decline in female-first authorship across scientific fields in 2020 due to the COVID-19 pandemic ( 23 , 24 ).

However, the results did not reach statistical significance after applying the Bonferroni correction, with a significance threshold set at P < 0.0125 (0.05/4).

A quantitative approach was employed which found a trend towards a reduction in bacterial stained area of 49.5% which did not reach statistical significance ( p = 0.015).

The differences between scores at baseline and subsequent weeks did not reach statistical significance (day 8: p = 0.015, day 15: p = 0.032) (Fig. 2 ).

While the difference did not reach statistical significance after Bonferroni correction, a marginal trend towards better survival was observed in the CTD-UIP group compared to the asbestosis-UIP group ( p = 0.017).

Mean PEG3 expression was lower in PatMS mice although this did not reach statistical significance after adjusting for multiple comparisons ( t = 2.690, P =0.018) ( Figure 2 D).

At 6 months after CA, both higher W/H ratio and BF% groups showed relatively larger LA size compared with their counterparts, but it did not reach statistical significance in BF% groups (W/H ratio: 34.2 ± 11.1 ml/m 2 vs 29.4 ± 8.7 ml/m 2 , P = 0.018, and BF%: 34.9 ± 10.8 ml/m 2 vs 30.8 ± 10.2 ml/m 2 , P = 0.060).

While a similar trend was seen when using the continuous exposure measure, the difference did not reach statistical significance (Table 3 , p = 0.018 with threshold of 0.017 after Bonferroni’s adjustment).

However, upon further adjustment for lifetime smoking, the effect sizes of the association slightly attenuated and did not reach statistical significance after Bonferroni correction (OR: 0.986; 95% CI: 0.975–0.998; p = 0.020) (Fig. 4 ).

Still, this difference did not reach statistical significance except in the group who were initiated on 10 mg daily of finerenone titrated up to 20 mg daily (hazard ratio 0.56, 95 % confidence interval 0.35–0.90, p = 0.02) [19] .

This outcome, whose individual components did not reach statistical significance, occurred in 35.5% of patients on treatment vs. 38.5% in the placebo group [relative risk (RR), 0.90; 95% confidence interval (CI), 0.82–0.98; P = 0.02]; 16.4% of patients on treatment and 17.5% of patients in the placebo arm died of cardiovascular causes (RR, 0.93; 95% CI, 0.81 to 1.06); 27.4% of patients on treatment and 29.6% in the placebo group were hospitalized for HF (RR, 0.90; 95% CI, 0.81–1.00).